Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual
Isotretinoin infrequently reported to be associated with the development and deterioration of myopia. Here we present a 37-year-old-woman on oral-isotretinoin-(20 mg/d)-for-acne-treatment presented with bilateral blurred vision and ocular pain for one week. Her UCVA was 20/200OD and 20/300OS. The re...
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Wolters Kluwer Medknow Publications
2024-01-01
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Series: | Al-Azhar Assiut Medical Journal |
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Online Access: | https://journals.lww.com/10.4103/azmj.azmj_51_22 |
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author | Abdallah E. Hammour |
author_facet | Abdallah E. Hammour |
author_sort | Abdallah E. Hammour |
collection | DOAJ |
description | Isotretinoin infrequently reported to be associated with the development and deterioration of myopia. Here we present a 37-year-old-woman on oral-isotretinoin-(20 mg/d)-for-acne-treatment presented with bilateral blurred vision and ocular pain for one week. Her UCVA was 20/200OD and 20/300OS. The refraction was−4.50Dâ 1.0D×180OD and−5.5Dâ 0.5D×30°OS. IOP was 68-mmHg. Slit-lamp examination revealed mild corneal edema, mid-dilated sluggish reaction pupils, and markedly shallow AC without inflammation. Gonioscopy-showed shallow AC with 360° appositional angle closure. Isotretinoin was discontinued, and anti-glaucoma and cycloplegic were started. A few days later all ocular manifestations were resolved. We think that an adverse reaction to oral isotretinoin may result in bilateral temporary myopia shift and acute secondary closed angle glaucoma. |
format | Article |
id | doaj-art-eda8c72ef7ca4424a08012d689f9d70f |
institution | Kabale University |
issn | 1687-1693 |
language | English |
publishDate | 2024-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Al-Azhar Assiut Medical Journal |
spelling | doaj-art-eda8c72ef7ca4424a08012d689f9d70f2025-01-17T15:48:56ZengWolters Kluwer Medknow PublicationsAl-Azhar Assiut Medical Journal1687-16932024-01-01221586110.4103/azmj.azmj_51_22Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individualAbdallah E. HammourIsotretinoin infrequently reported to be associated with the development and deterioration of myopia. Here we present a 37-year-old-woman on oral-isotretinoin-(20 mg/d)-for-acne-treatment presented with bilateral blurred vision and ocular pain for one week. Her UCVA was 20/200OD and 20/300OS. The refraction was−4.50Dâ 1.0D×180OD and−5.5Dâ 0.5D×30°OS. IOP was 68-mmHg. Slit-lamp examination revealed mild corneal edema, mid-dilated sluggish reaction pupils, and markedly shallow AC without inflammation. Gonioscopy-showed shallow AC with 360° appositional angle closure. Isotretinoin was discontinued, and anti-glaucoma and cycloplegic were started. A few days later all ocular manifestations were resolved. We think that an adverse reaction to oral isotretinoin may result in bilateral temporary myopia shift and acute secondary closed angle glaucoma.https://journals.lww.com/10.4103/azmj.azmj_51_22acneclosed angle glaucomaisotretinoin medicationmyopia |
spellingShingle | Abdallah E. Hammour Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual Al-Azhar Assiut Medical Journal acne closed angle glaucoma isotretinoin medication myopia |
title | Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual |
title_full | Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual |
title_fullStr | Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual |
title_full_unstemmed | Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual |
title_short | Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual |
title_sort | isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual |
topic | acne closed angle glaucoma isotretinoin medication myopia |
url | https://journals.lww.com/10.4103/azmj.azmj_51_22 |
work_keys_str_mv | AT abdallahehammour isoteritinoininducedtransientmyopiaandacutesecondaryclosedangleglaucomainahealthyindividual |