Isoteritinoin induced transient myopia and acute secondary closed angle glaucoma in a healthy individual

Isotretinoin infrequently reported to be associated with the development and deterioration of myopia. Here we present a 37-year-old-woman on oral-isotretinoin-(20 mg/d)-for-acne-treatment presented with bilateral blurred vision and ocular pain for one week. Her UCVA was 20/200OD and 20/300OS. The re...

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Bibliographic Details
Main Author: Abdallah E. Hammour
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Al-Azhar Assiut Medical Journal
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Online Access:https://journals.lww.com/10.4103/azmj.azmj_51_22
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Summary:Isotretinoin infrequently reported to be associated with the development and deterioration of myopia. Here we present a 37-year-old-woman on oral-isotretinoin-(20 mg/d)-for-acne-treatment presented with bilateral blurred vision and ocular pain for one week. Her UCVA was 20/200OD and 20/300OS. The refraction was−4.50Dâ 1.0D×180OD and−5.5Dâ 0.5D×30°OS. IOP was 68-mmHg. Slit-lamp examination revealed mild corneal edema, mid-dilated sluggish reaction pupils, and markedly shallow AC without inflammation. Gonioscopy-showed shallow AC with 360° appositional angle closure. Isotretinoin was discontinued, and anti-glaucoma and cycloplegic were started. A few days later all ocular manifestations were resolved. We think that an adverse reaction to oral isotretinoin may result in bilateral temporary myopia shift and acute secondary closed angle glaucoma.
ISSN:1687-1693