NITROIMIDAZOLES XI [I]. SYNTHESES OF DISUBSTITUTED NITROIMIDAZOLYLQUINOLINES
Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-...
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| Format: | Article |
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| Language: | English |
| Published: |
University of Tehran
1995-03-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
| Online Access: | https://jsciences.ut.ac.ir/article_31214_0a680a6106e6ebc4895e6d68a4826418.pdf |
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| Summary: | Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2-
carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)-
substituted-quinolines (lo), which were converted to compound 11 with
phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.-
methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2-
acetyl-5-nitro-1-methyl-imidazole (13) with 0-aminoacetophenones (or Oaminobenzophenones)
in acid medium |
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| ISSN: | 1016-1104 2345-6914 |