Copper Increases the Cooperative Gating of Rat P2X2a Receptor Channels

Copper Increases the Cooperative Gating of Rat P2X2a Receptor Channels

<b>Background/Objectives:</b> P2X receptor channels are widely expressed in the CNS, where they have multiple functions in health and disease. The rat P2X2a (rP2X2a) receptor channel is modulated by copper, an essential trace element that plays important roles in synaptic modulation and...

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Bibliographic Details
Main Authors: Elias Leiva-Salcedo, Denise Riquelme, Juan Pablo Huidobro-Toro, Claudio Coddou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
cooperativity
P2X2
P2X2a
single channel
copper
trace metals
Online Access:https://www.mdpi.com/1424-8247/17/12/1590
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