Overexpression of tRNA m7G modification methyltransferase complex promotes the biosynthesis of triterpene in yeast

Overexpression of tRNA m7G modification methyltransferase complex promotes the biosynthesis of triterpene in yeast

BackgroundThe sustainable production of valuable compounds using microbial cell factories is an effective approach, yet further metabolic engineering strategies are needed to enhance their biosynthetic potential. Recent studies suggest that RNA modifications can influence cellular metabolism, but th...

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Bibliographic Details
Main Authors: Mengyu Ma, Jun Wang, Zhengwei Tan, Xiqin Liang, Bengui Fan, Lei Li, Huizhen Liang, Tianyue An, Guoli Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
tRNA m7G modification
metabolic engineering
terpenoids
transcriptome analysis
Saccharomyces cerevisiae
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1557443/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1557443/full

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