APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION
Different angiogenic factors induced angiogenesis stimulation in ischemic tissues stays in the focus of scientific research for long time. The key role in ischemic angiogenesis belongs to endothelial precursor cells, plenty of which are reserved in bone marrow. Resident endothelial precursor cells a...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2010-06-01
|
| Series: | Вестник трансплантологии и искусственных органов |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/296 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849242097212719104 |
|---|---|
| author | M. V. Eremeeva |
| author_facet | M. V. Eremeeva |
| author_sort | M. V. Eremeeva |
| collection | DOAJ |
| description | Different angiogenic factors induced angiogenesis stimulation in ischemic tissues stays in the focus of scientific research for long time. The key role in ischemic angiogenesis belongs to endothelial precursor cells, plenty of which are reserved in bone marrow. Resident endothelial precursor cells are also found in some tissues and in circulation. These cells are involved in neoangiogenesis as well. Theoretically, injection of exogeneous endothelial precusor cells might contribute to restoration of circulation in the ischemic organ. Various types of cells have been approved for regeneration stimulation in a number of experimental protocols. A various degree of improvement of myocardial contractive function has been obtained as a universal result of these investigations, though the mechanisms underlying observed effect remain evasive. The paper focuses on advantages and drawbacks of embryonic, hematopoetic and mesenhimal stem cells application for angiogenesis stimulation and organs and tissues regeneration. |
| format | Article |
| id | doaj-art-ed3a37db12c04a6c9e47a11bc8d08950 |
| institution | Kabale University |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2010-06-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-ed3a37db12c04a6c9e47a11bc8d089502025-08-20T03:59:56ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912010-06-01121869310.15825/1995-1191-2010-1-86-93239APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATIONM. V. Eremeeva0A.N. Bakulev Scientific Center of Cardiovascular Surgery, RAMS, MoscowDifferent angiogenic factors induced angiogenesis stimulation in ischemic tissues stays in the focus of scientific research for long time. The key role in ischemic angiogenesis belongs to endothelial precursor cells, plenty of which are reserved in bone marrow. Resident endothelial precursor cells are also found in some tissues and in circulation. These cells are involved in neoangiogenesis as well. Theoretically, injection of exogeneous endothelial precusor cells might contribute to restoration of circulation in the ischemic organ. Various types of cells have been approved for regeneration stimulation in a number of experimental protocols. A various degree of improvement of myocardial contractive function has been obtained as a universal result of these investigations, though the mechanisms underlying observed effect remain evasive. The paper focuses on advantages and drawbacks of embryonic, hematopoetic and mesenhimal stem cells application for angiogenesis stimulation and organs and tissues regeneration.https://journal.transpl.ru/vtio/article/view/296neoangiogenesismyocardial regenerationembryonic stem cellshematopoetic stem cellsmesenhimal stem cell |
| spellingShingle | M. V. Eremeeva APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION Вестник трансплантологии и искусственных органов neoangiogenesis myocardial regeneration embryonic stem cells hematopoetic stem cells mesenhimal stem cell |
| title | APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION |
| title_full | APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION |
| title_fullStr | APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION |
| title_full_unstemmed | APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION |
| title_short | APPLICATION OF STEM CELLS AND PRECURSOR CELLS FOR STIMULATION OF ORGAN REVASCULARIZATION AND REGENERATION |
| title_sort | application of stem cells and precursor cells for stimulation of organ revascularization and regeneration |
| topic | neoangiogenesis myocardial regeneration embryonic stem cells hematopoetic stem cells mesenhimal stem cell |
| url | https://journal.transpl.ru/vtio/article/view/296 |
| work_keys_str_mv | AT mveremeeva applicationofstemcellsandprecursorcellsforstimulationoforganrevascularizationandregeneration |