Oxidative Stress-Induced Diseases via the ASK1 Signaling Pathway

Oxidative Stress-Induced Diseases via the ASK1 Signaling Pathway

Apoptosis signal-regulating kinase 1 (ASK1) is a mitogen-activated protein kinase (MAPK) kinase kinase that activates the downstream MAPKs, c-Jun N-terminal kinase (JNK) and p38. ASK1 is activated by various types of stress, such as oxidative stress, endoplasmic reticulum stress, and infection, and...

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Bibliographic Details
Main Authors: Mayumi Soga, Atsushi Matsuzawa, Hidenori Ichijo
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/439587
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