How the Topology of the Mitochondrial Inner Membrane Modulates ATP Production

Cells in heart muscle need to generate ATP at or near peak capacity to meet their energy demands. Over 90% of this ATP comes from mitochondria, strategically located near myofibrils and densely packed with cristae to concentrate ATP generation per unit volume. However, a consequence of dense inner m...

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Bibliographic Details
Main Authors: Raquel Adams, Nasrin Afzal, Mohsin Saleet Jafri, Carmen A. Mannella
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/4/257
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