Journey through tumorverse: Creating models to decode PXA mysteries

Pleomorphic xanthoastrocytoma (PXA) is a rare pediatric low-grade glioma (pLGG), of which 60%–80% exhibit the BRAF V600E mutation, that enhances the aggressiveness and progression to an eventual pediatric high-grade glioma (pHGG). Despite the aggressiveness of this mutational status, the mechanisms...

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Bibliographic Details
Main Authors: George Bukenya, Anthony R. Sloan, Justin D. Lathia
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Molecular Therapy: Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S295032992400095X
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