Isolation of cancer stem like cells from human adenosquamous carcinoma of the lung supports a monoclonal origin from a multipotential tissue stem cell.

There is increasing evidence that many solid tumors are hierarchically organized with the bulk tumor cells having limited replication potential, but are sustained by a stem-like cell that perpetuates the tumor. These cancer stem cells have been hypothesized to originate from transformation of adult...

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Bibliographic Details
Main Authors: Jennie P Mather, Penelope E Roberts, Zhuangyu Pan, Francine Chen, Jeffrey Hooley, Peter Young, Xiaolin Xu, Douglas H Smith, Ann Easton, Panjing Li, Ezio Bonvini, Scott Koenig, Paul A Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0079456&type=printable
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