Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation

Psoriasis vulgaris incidence in Italy is 2%–3%, 0.1% with severe forms with systemic erythema, risk of skin cancer, and hypercoagulation disorders. These patients are a challenging cohort for free-tissue transfer reconstructions. We present a 47-year-old woman with a history of generalized uncontrol...

Full description

Saved in:
Bibliographic Details
Main Authors: Tamburello Sara, Guido Mauro, Francesco Mori, Menichini Giulio
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Dermatology and Dermatologic Surgery
Subjects:
Online Access:https://journals.lww.com/10.4103/jdds.jdds_56_23
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841556610263023616
author Tamburello Sara
Guido Mauro
Francesco Mori
Menichini Giulio
author_facet Tamburello Sara
Guido Mauro
Francesco Mori
Menichini Giulio
author_sort Tamburello Sara
collection DOAJ
description Psoriasis vulgaris incidence in Italy is 2%–3%, 0.1% with severe forms with systemic erythema, risk of skin cancer, and hypercoagulation disorders. These patients are a challenging cohort for free-tissue transfer reconstructions. We present a 47-year-old woman with a history of generalized uncontrolled pustular psoriasis with an infiltrative squamocellular carcinoma of the forearm of 5 cm × 3 cm. We offered a reconstructive approach with vascularized fibular intercalary reconstruction of the ulna and a combined anterolateral thigh flap for the soft-tissue defect. The surgical outcome was complicated by incoercible vasospasm, arterial thrombosis, and free-flap failure. We decided to review the literature and formulate a therapeutic protocol to tackle the critical aspects of psoriasis impacting on free-flap viability before reintervention. Eventually, the outcome was successful. No article was available putting in relation to these two aspects. We believe this is the first article of its kind and would be a starting point for further studies.
format Article
id doaj-art-ec93d3743878462f978c16a788d53cd3
institution Kabale University
issn 2352-2410
2352-2429
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Dermatology and Dermatologic Surgery
spelling doaj-art-ec93d3743878462f978c16a788d53cd32025-01-07T06:53:12ZengWolters Kluwer Medknow PublicationsJournal of Dermatology and Dermatologic Surgery2352-24102352-24292024-12-0128211211510.4103/jdds.jdds_56_23Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and MicrocirculationTamburello SaraGuido MauroFrancesco MoriMenichini GiulioPsoriasis vulgaris incidence in Italy is 2%–3%, 0.1% with severe forms with systemic erythema, risk of skin cancer, and hypercoagulation disorders. These patients are a challenging cohort for free-tissue transfer reconstructions. We present a 47-year-old woman with a history of generalized uncontrolled pustular psoriasis with an infiltrative squamocellular carcinoma of the forearm of 5 cm × 3 cm. We offered a reconstructive approach with vascularized fibular intercalary reconstruction of the ulna and a combined anterolateral thigh flap for the soft-tissue defect. The surgical outcome was complicated by incoercible vasospasm, arterial thrombosis, and free-flap failure. We decided to review the literature and formulate a therapeutic protocol to tackle the critical aspects of psoriasis impacting on free-flap viability before reintervention. Eventually, the outcome was successful. No article was available putting in relation to these two aspects. We believe this is the first article of its kind and would be a starting point for further studies.https://journals.lww.com/10.4103/jdds.jdds_56_23complicationsfree-flapmicrosurgerypsoriasissquamocellular carcinoma
spellingShingle Tamburello Sara
Guido Mauro
Francesco Mori
Menichini Giulio
Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation
Journal of Dermatology and Dermatologic Surgery
complications
free-flap
microsurgery
psoriasis
squamocellular carcinoma
title Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation
title_full Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation
title_fullStr Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation
title_full_unstemmed Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation
title_short Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation
title_sort infiltrative squamocellular carcinoma of the forearm in a patient with uncontrolled psoriasis impact on microsurgical flap viability and microcirculation
topic complications
free-flap
microsurgery
psoriasis
squamocellular carcinoma
url https://journals.lww.com/10.4103/jdds.jdds_56_23
work_keys_str_mv AT tamburellosara infiltrativesquamocellularcarcinomaoftheforearminapatientwithuncontrolledpsoriasisimpactonmicrosurgicalflapviabilityandmicrocirculation
AT guidomauro infiltrativesquamocellularcarcinomaoftheforearminapatientwithuncontrolledpsoriasisimpactonmicrosurgicalflapviabilityandmicrocirculation
AT francescomori infiltrativesquamocellularcarcinomaoftheforearminapatientwithuncontrolledpsoriasisimpactonmicrosurgicalflapviabilityandmicrocirculation
AT menichinigiulio infiltrativesquamocellularcarcinomaoftheforearminapatientwithuncontrolledpsoriasisimpactonmicrosurgicalflapviabilityandmicrocirculation