Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020
Background: Toxoplasmosis is a disease caused by an obligate intracellular protozoan called Toxoplasma gondii. Consumption of raw or undercooked meat infected with tissue cysts and consumption of parasite oocysts are considered the main ways of parasite transmission to humans. The most severe compli...
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Ardabil University of Medical Sciences
2024-07-01
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| Series: | Journal of Ardabil University of Medical Sciences |
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| Online Access: | http://jarums.arums.ac.ir/article-1-2440-en.pdf |
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| author | Roya Houshmandi Khaneghahi Shahram Habibzadeh Farhad Pourfarzi Behnam Mohammadi Ghalehbin |
| author_facet | Roya Houshmandi Khaneghahi Shahram Habibzadeh Farhad Pourfarzi Behnam Mohammadi Ghalehbin |
| author_sort | Roya Houshmandi Khaneghahi |
| collection | DOAJ |
| description | Background: Toxoplasmosis is a disease caused by an obligate intracellular protozoan called Toxoplasma gondii. Consumption of raw or undercooked meat infected with tissue cysts and consumption of parasite oocysts are considered the main ways of parasite transmission to humans. The most severe complications of toxoplasmosis occur in people who have an ineffective immune system, as well as during pregnancy. Since the awareness of the prevalence of toxoplasmosis in different population groups and geographical areas and the risk factors involved in it, is one of the most important indicators which can be estimated the risk of infection in any society, this study aims to know the extent of prevalence of anti-toxoplasma antibody in serum and some risk factors related to it in females in Ardabil city.
Methods: Three hundred forty nine female of Ardabil city were randomly selected based on the files available in health centers. This number was divided into ten-year age groups with an age range of 1-69 years. These people were invited and included in the study if they agreed. The designed questionnaire was completed and blood samples were taken. Serum samples were tested using an ELISA kit to detect anti-Toxoplasma IgG antibody.
Results: The prevalence rate of anti-toxoplasma IgG antibody in female residents in Ardabil, aged 1 to 69 years was 45%. The prevalence rate was directly related to increasing age. People’s education level had an inverse relationship with the infection rate. Despite the increase in seropositivity, the prevalence rate in people who had contact with cats was not significant. Also, the prevalence rate had a direct and significant relationship with increasing BMI.
Conclusion: The seroprevalence of anti-toxoplasmosis antibody in female people in Ardabil is equal to 45% and is high compared to the world estimates. 70-75% of people of marriageable age are seronegative and are at risk of contracting acute toxoplasmosis during pregnancy, which requires appropriate preventive health policies. |
| format | Article |
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| institution | Kabale University |
| issn | 2228-7280 2228-7299 |
| language | fas |
| publishDate | 2024-07-01 |
| publisher | Ardabil University of Medical Sciences |
| record_format | Article |
| series | Journal of Ardabil University of Medical Sciences |
| spelling | doaj-art-ec45b95cdce54fb5a9842a560918544f2025-01-16T07:22:32ZfasArdabil University of Medical SciencesJournal of Ardabil University of Medical Sciences2228-72802228-72992024-07-01242221231Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020Roya Houshmandi Khaneghahi0Shahram Habibzadeh1Farhad Pourfarzi2Behnam Mohammadi Ghalehbin3 General Practitioner, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Department of Infectious Diseases, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Digestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran Department of Microbiology and Medical Parasitology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Background: Toxoplasmosis is a disease caused by an obligate intracellular protozoan called Toxoplasma gondii. Consumption of raw or undercooked meat infected with tissue cysts and consumption of parasite oocysts are considered the main ways of parasite transmission to humans. The most severe complications of toxoplasmosis occur in people who have an ineffective immune system, as well as during pregnancy. Since the awareness of the prevalence of toxoplasmosis in different population groups and geographical areas and the risk factors involved in it, is one of the most important indicators which can be estimated the risk of infection in any society, this study aims to know the extent of prevalence of anti-toxoplasma antibody in serum and some risk factors related to it in females in Ardabil city. Methods: Three hundred forty nine female of Ardabil city were randomly selected based on the files available in health centers. This number was divided into ten-year age groups with an age range of 1-69 years. These people were invited and included in the study if they agreed. The designed questionnaire was completed and blood samples were taken. Serum samples were tested using an ELISA kit to detect anti-Toxoplasma IgG antibody. Results: The prevalence rate of anti-toxoplasma IgG antibody in female residents in Ardabil, aged 1 to 69 years was 45%. The prevalence rate was directly related to increasing age. People’s education level had an inverse relationship with the infection rate. Despite the increase in seropositivity, the prevalence rate in people who had contact with cats was not significant. Also, the prevalence rate had a direct and significant relationship with increasing BMI. Conclusion: The seroprevalence of anti-toxoplasmosis antibody in female people in Ardabil is equal to 45% and is high compared to the world estimates. 70-75% of people of marriageable age are seronegative and are at risk of contracting acute toxoplasmosis during pregnancy, which requires appropriate preventive health policies.http://jarums.arums.ac.ir/article-1-2440-en.pdftoxoplasmosisseroepidemiological studyardabil |
| spellingShingle | Roya Houshmandi Khaneghahi Shahram Habibzadeh Farhad Pourfarzi Behnam Mohammadi Ghalehbin Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 Journal of Ardabil University of Medical Sciences toxoplasmosis seroepidemiological study ardabil |
| title | Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 |
| title_full | Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 |
| title_fullStr | Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 |
| title_full_unstemmed | Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 |
| title_short | Seroepidemiological Study of Human Toxoplasmosis in Females in Ardabil City, 2019-2020 |
| title_sort | seroepidemiological study of human toxoplasmosis in females in ardabil city 2019 2020 |
| topic | toxoplasmosis seroepidemiological study ardabil |
| url | http://jarums.arums.ac.ir/article-1-2440-en.pdf |
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