Mutational spectrum of BRCA genes in Egyptian patients with breast cancer

Mutational spectrum of BRCA genes in Egyptian patients with breast cancer

Abstract The rising incidence of breast cancer (BC) among Egyptian females with a mortality rate of 11% and younger age at diagnosis implied the study of the interplay of BRCA gene variants with other BC risk factors. The study enrolled 500 BC Egyptian females with a mean age of 47.29 ± 13.26 years...

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Bibliographic Details
Main Authors: Wafaa Elmetnawy, Heba Nader, Tamer ElNahas, Salwa Sabet, Heba Bassiony, Yasser ElNahass
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
BRCA1/2
Breast cancer
Family history
HR+ 
HR−
TNBC
Online Access:https://doi.org/10.1038/s41598-025-09810-5
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