Structural basis for full-length chemerin recognition and signaling through chemerin receptor 1
Abstract Chemerin, a chemotactic adipokine, plays essential roles in adipogenesis and inflammation. Serum chemerin concentration is closely associated with obesity and metabolism disorders. The mature form of chemerin (residues 21-157) acts primarily through chemerin receptor 1 (CMKLR1) for transmem...
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| Main Authors: | Aijun Liu, Yezhou Liu, Junlin Wang, Richard D. Ye |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-024-07228-9 |
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