Impact of Daily Lower‐Body Negative Pressure or Cycling Followed by Venous Constrictive Thigh Cuffs on Bedrest‐Induced Orthostatic Intolerance

Impact of Daily Lower‐Body Negative Pressure or Cycling Followed by Venous Constrictive Thigh Cuffs on Bedrest‐Induced Orthostatic Intolerance

Background Orthostatic intolerance occurs following immobilization in patients on Earth and in astronauts after spaceflight. Head‐down tilt bedrest is a terrestrial model for weightlessness and induces orthostatic intolerance. We hypothesized that lower‐body negative pressure (LBNP) or cycling follo...

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Bibliographic Details
Main Authors: Jan‐Niklas Hönemann, Fabian Hoffmann, Laura de Boni, Peter Gauger, Edwin Mulder, Stefan Möstl, Karsten Heusser, Marie‐Therese Schmitz, Marcel Halbach, Steven S. Laurie, Stuart M. C. Lee, Brandon R. Macias, Jens Jordan, Jens Tank
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
bedrest
countermeasures
hemodynamics
orthostatic tolerance
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.034800
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