Construction of oncolytic reporter influenza viral vectors and assessment of their safety following intracranial administration in rats

Construction of oncolytic reporter influenza viral vectors and assessment of their safety following intracranial administration in rats

INTRODUCTION: Oncolytic viruses are a promising approach for treating malignant brain tumors as part a of combination therapy. OBJECTIVE: To develop reporter influenza A viruses expressing NanoLuc luciferase and evaluate their safety following intracranial administration in rats. METHODS: Chemilu...

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Main Authors: A. A. Pulkina, A. S. Mustafaeva, E. A. Romanovskaya-Romanko, M. A. Plotnikova, O. O. Ozhereleva, M. A. Shuklina, L. N. Kiseleva, Y. S. Alekseeva, N. S. Kurmazov, A. R. Muslimov, A.-P.S. Shurygina, M. A. Stukova
Format: Article
Language:English
Published: Doctrine 2024-11-01
Series:Microbiology Independent Research Journal
Online Access:https://www.scienceopen.com/hosted-document?doi=10.18527/202411105118
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