Bindarit attenuates neuroinflammation after subarachnoid hemorrhage by regulating the CCL2/CCR2/NF-κB pathway

Bindarit attenuates neuroinflammation after subarachnoid hemorrhage by regulating the CCL2/CCR2/NF-κB pathway

Background and purpose: The poor prognosis of subarachnoid hemorrhage (SAH) is closely linked to neuroinflammation and neuronal apoptosis. The CCL2/CCR2 signaling axis, a cytoplasmic pathway responsible for recruiting immune cells, plays a significant role in regulating neuroinflammation in neurolog...

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Bibliographic Details
Main Authors: Yanting Yao, Qiaowei Wu, Kaikun Yuan, Pei Wu, Chao Xu, Zhiyong Ji, Weishi Xu, Hongli Yu, Anyu Xu, Yanchen Liu, Huaizhang Shi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain Research Bulletin
Subjects:
Subarachnoid hemorrhage
Bindarit
CCL2/CCR2
Neuroinflammation
Apoptosis
Microglia polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923024003174
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