Understanding CO adsorption in MOFs combining atomic simulations and machine learning

Abstract This study introduces a computational method integrating molecular simulations and machine learning (ML) to assess the CO adsorption capacities of synthesized and hypothetical metal–organic frameworks (MOFs) at various pressures. After extracting structural, chemical, and energy-based featu...

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Main Authors: Goktug Ercakir, Gokhan Onder Aksu, Seda Keskin
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-76491-x
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author Goktug Ercakir
Gokhan Onder Aksu
Seda Keskin
author_facet Goktug Ercakir
Gokhan Onder Aksu
Seda Keskin
author_sort Goktug Ercakir
collection DOAJ
description Abstract This study introduces a computational method integrating molecular simulations and machine learning (ML) to assess the CO adsorption capacities of synthesized and hypothetical metal–organic frameworks (MOFs) at various pressures. After extracting structural, chemical, and energy-based features of the synthesized and hypothetical MOFs (hMOFs), we conducted molecular simulations to compute CO adsorption in synthesized MOFs and used these simulation results to train ML models for predicting CO adsorption in hMOFs. Results showed that CO uptakes of synthesized MOFs and hMOFs are between 0.02–2.28 mol/kg and 0.45–3.06 mol/kg, respectively, at 1 bar, 298 K. At low pressures (0.1 and 1 bar), Henry’s constant of CO is the most dominant feature, whereas structural properties such as surface area and porosity are more influential for determining the CO uptakes of MOFs at high pressure (10 bar). Structural and chemical analyses revealed that MOFs with narrow pores (4.4–7.3 Å), aromatic ring-containing linkers and carboxylic acid groups, along with metal nodes such as Co, Zn, Ni achieve high CO uptakes at 1 bar. Our approach evaluated the CO uptakes of ~ 100,000 MOFs, the most extensive and diverse set studied for CO capture thus far, as a robust alternative to computationally demanding molecular simulations and iterative experiments.
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spelling doaj-art-eaa25d4477d645c8868a53f3864ef4032024-12-22T12:25:41ZengNature PortfolioScientific Reports2045-23222024-10-0114111210.1038/s41598-024-76491-xUnderstanding CO adsorption in MOFs combining atomic simulations and machine learningGoktug Ercakir0Gokhan Onder Aksu1Seda Keskin2Department of Chemical and Biological Engineering, Koç UniversityDepartment of Chemical and Biological Engineering, Koç UniversityDepartment of Chemical and Biological Engineering, Koç UniversityAbstract This study introduces a computational method integrating molecular simulations and machine learning (ML) to assess the CO adsorption capacities of synthesized and hypothetical metal–organic frameworks (MOFs) at various pressures. After extracting structural, chemical, and energy-based features of the synthesized and hypothetical MOFs (hMOFs), we conducted molecular simulations to compute CO adsorption in synthesized MOFs and used these simulation results to train ML models for predicting CO adsorption in hMOFs. Results showed that CO uptakes of synthesized MOFs and hMOFs are between 0.02–2.28 mol/kg and 0.45–3.06 mol/kg, respectively, at 1 bar, 298 K. At low pressures (0.1 and 1 bar), Henry’s constant of CO is the most dominant feature, whereas structural properties such as surface area and porosity are more influential for determining the CO uptakes of MOFs at high pressure (10 bar). Structural and chemical analyses revealed that MOFs with narrow pores (4.4–7.3 Å), aromatic ring-containing linkers and carboxylic acid groups, along with metal nodes such as Co, Zn, Ni achieve high CO uptakes at 1 bar. Our approach evaluated the CO uptakes of ~ 100,000 MOFs, the most extensive and diverse set studied for CO capture thus far, as a robust alternative to computationally demanding molecular simulations and iterative experiments.https://doi.org/10.1038/s41598-024-76491-xMetal–organic framework (MOF)Carbon monoxide (CO)AdsorptionMolecular simulationMachine learning
spellingShingle Goktug Ercakir
Gokhan Onder Aksu
Seda Keskin
Understanding CO adsorption in MOFs combining atomic simulations and machine learning
Scientific Reports
Metal–organic framework (MOF)
Carbon monoxide (CO)
Adsorption
Molecular simulation
Machine learning
title Understanding CO adsorption in MOFs combining atomic simulations and machine learning
title_full Understanding CO adsorption in MOFs combining atomic simulations and machine learning
title_fullStr Understanding CO adsorption in MOFs combining atomic simulations and machine learning
title_full_unstemmed Understanding CO adsorption in MOFs combining atomic simulations and machine learning
title_short Understanding CO adsorption in MOFs combining atomic simulations and machine learning
title_sort understanding co adsorption in mofs combining atomic simulations and machine learning
topic Metal–organic framework (MOF)
Carbon monoxide (CO)
Adsorption
Molecular simulation
Machine learning
url https://doi.org/10.1038/s41598-024-76491-x
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AT gokhanonderaksu understandingcoadsorptioninmofscombiningatomicsimulationsandmachinelearning
AT sedakeskin understandingcoadsorptioninmofscombiningatomicsimulationsandmachinelearning