Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It

The concept of translational gap implies that the intensive development of basic biomedical research at the turn of the 20th and 21st centuries has not, until recently, been accompanied by a proportional increase in the number of innovative drugs, as well as diagnostic and therapeutic technologies t...

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Main Author: M. M. Galagudza
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2025-07-01
Series:Регуляторные исследования и экспертиза лекарственных средств
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Online Access:https://www.vedomostincesmp.ru/jour/article/view/791
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author M. M. Galagudza
author_facet M. M. Galagudza
author_sort M. M. Galagudza
collection DOAJ
description The concept of translational gap implies that the intensive development of basic biomedical research at the turn of the 20th and 21st centuries has not, until recently, been accompanied by a proportional increase in the number of innovative drugs, as well as diagnostic and therapeutic technologies that have found application in clinical practice. Mikhail M. Galagudza, Director of the Institute of Experimental Medicine at the Almazov National Medical Research Center of the Russian Ministry of Healthcare, Doctor of Medical Sciences, Professor and Corresponding Member of the Russian Academy of Sciences, shares his thoughts on the causes of the translational crisis and ways of its resolution.
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institution Kabale University
issn 3034-3062
3034-3453
language Russian
publishDate 2025-07-01
publisher Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)
record_format Article
series Регуляторные исследования и экспертиза лекарственных средств
spelling doaj-art-ea931afe6a1c40c2b23440a24f85b48d2025-08-20T03:57:31ZrusFederal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)Регуляторные исследования и экспертиза лекарственных средств3034-30623034-34532025-07-0115310.30895/1991-2919-2025-15-3-248-251527Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome ItM. M. Galagudza0National Medical Research Center named after V.A. AlmazovThe concept of translational gap implies that the intensive development of basic biomedical research at the turn of the 20th and 21st centuries has not, until recently, been accompanied by a proportional increase in the number of innovative drugs, as well as diagnostic and therapeutic technologies that have found application in clinical practice. Mikhail M. Galagudza, Director of the Institute of Experimental Medicine at the Almazov National Medical Research Center of the Russian Ministry of Healthcare, Doctor of Medical Sciences, Professor and Corresponding Member of the Russian Academy of Sciences, shares his thoughts on the causes of the translational crisis and ways of its resolution.https://www.vedomostincesmp.ru/jour/article/view/791biomedicinedevelopmenttranslational researchtranslational crisisdata reproducibilitypreclinical studies
spellingShingle M. M. Galagudza
Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It
Регуляторные исследования и экспертиза лекарственных средств
biomedicine
development
translational research
translational crisis
data reproducibility
preclinical studies
title Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It
title_full Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It
title_fullStr Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It
title_full_unstemmed Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It
title_short Translational Crisis in Biomedical Research: Analysis of Causes and Ways to Overcome It
title_sort translational crisis in biomedical research analysis of causes and ways to overcome it
topic biomedicine
development
translational research
translational crisis
data reproducibility
preclinical studies
url https://www.vedomostincesmp.ru/jour/article/view/791
work_keys_str_mv AT mmgalagudza translationalcrisisinbiomedicalresearchanalysisofcausesandwaystoovercomeit