Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis

Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis

ObjectiveEstablishing biomarkers to predict multiple sclerosis (MS) disability accrual has been challenging using a single biomarker approach, likely due to the complex interplay of neuroinflammation and neurodegeneration. Here, we aimed to investigate the prognostic value of single and multimodal b...

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Bibliographic Details
Main Authors: Vinzenz Fleischer, Tobias Brummer, Muthuraman Muthuraman, Falk Steffen, Milena Heldt, Maria Protopapa, Muriel Schraad, Gabriel Gonzalez-Escamilla, Sergiu Groppa, Stefan Bittner, Frauke Zipp
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
biomarker
magnetic resonance imaging
neurofilament
optical coherence tomography
disease progression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1532660/full
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