Inflammatory bowel disease – one entity with many molecular faces
Inflammatory bowel disease (IBD) is a heterogenous group of chronic inflammations in the gastrointestinal tract, which traditionally consists of two types: Crohn’s disease and ulcerative colitis. They differ when it comes to clinical, endoscopic, and histopathological changes. The exact aetiology of...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2019-12-01
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| Series: | Gastroenterology Review |
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| Online Access: | https://www.termedia.pl/Inflammatory-bowel-disease-one-entity-with-many-molecular-faces,41,38784,1,1.html |
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| _version_ | 1841548354405793792 |
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| author | Sylwia Szymańska Malgorzata Matuszczyk Magdalena Osuch Monika Meglicka Edyta Szymanska Joanna Bierła Jaroslaw Kierkuś |
| author_facet | Sylwia Szymańska Malgorzata Matuszczyk Magdalena Osuch Monika Meglicka Edyta Szymanska Joanna Bierła Jaroslaw Kierkuś |
| author_sort | Sylwia Szymańska |
| collection | DOAJ |
| description | Inflammatory bowel disease (IBD) is a heterogenous group of chronic inflammations in the gastrointestinal tract, which traditionally consists of two types: Crohn’s disease and ulcerative colitis. They differ when it comes to clinical, endoscopic, and histopathological changes. The exact aetiology of IBD has not been fully comprehended, but what is known so far is that the aetiopathogenesis of the disease is compound. Many articles have been written on the cellular/molecular background of IBD. Based on various molecular pathways, new forms of the disease have been discovered, including very early-onset IBD (VEO-IBD) or IBD coexisting with primary sclerosing cholangitis. The aim of this article is to present the molecular mechanisms leading to IBD, focusing on new forms of this disorder. |
| format | Article |
| id | doaj-art-ea69a8269db3437187f4de3a0dc1f13a |
| institution | Kabale University |
| issn | 1895-5770 1897-4317 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Gastroenterology Review |
| spelling | doaj-art-ea69a8269db3437187f4de3a0dc1f13a2025-01-10T14:06:16ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172019-12-0114422823210.5114/pg.2019.9024938784Inflammatory bowel disease – one entity with many molecular facesSylwia SzymańskaMalgorzata MatuszczykMagdalena OsuchMonika MeglickaEdyta SzymanskaJoanna BierłaJaroslaw KierkuśInflammatory bowel disease (IBD) is a heterogenous group of chronic inflammations in the gastrointestinal tract, which traditionally consists of two types: Crohn’s disease and ulcerative colitis. They differ when it comes to clinical, endoscopic, and histopathological changes. The exact aetiology of IBD has not been fully comprehended, but what is known so far is that the aetiopathogenesis of the disease is compound. Many articles have been written on the cellular/molecular background of IBD. Based on various molecular pathways, new forms of the disease have been discovered, including very early-onset IBD (VEO-IBD) or IBD coexisting with primary sclerosing cholangitis. The aim of this article is to present the molecular mechanisms leading to IBD, focusing on new forms of this disorder.https://www.termedia.pl/Inflammatory-bowel-disease-one-entity-with-many-molecular-faces,41,38784,1,1.htmlinflammatory bowel disease crohn’s disease ulcerative colitis genetics molecular pathways |
| spellingShingle | Sylwia Szymańska Malgorzata Matuszczyk Magdalena Osuch Monika Meglicka Edyta Szymanska Joanna Bierła Jaroslaw Kierkuś Inflammatory bowel disease – one entity with many molecular faces Gastroenterology Review inflammatory bowel disease crohn’s disease ulcerative colitis genetics molecular pathways |
| title | Inflammatory bowel disease – one entity with many molecular faces |
| title_full | Inflammatory bowel disease – one entity with many molecular faces |
| title_fullStr | Inflammatory bowel disease – one entity with many molecular faces |
| title_full_unstemmed | Inflammatory bowel disease – one entity with many molecular faces |
| title_short | Inflammatory bowel disease – one entity with many molecular faces |
| title_sort | inflammatory bowel disease one entity with many molecular faces |
| topic | inflammatory bowel disease crohn’s disease ulcerative colitis genetics molecular pathways |
| url | https://www.termedia.pl/Inflammatory-bowel-disease-one-entity-with-many-molecular-faces,41,38784,1,1.html |
| work_keys_str_mv | AT sylwiaszymanska inflammatoryboweldiseaseoneentitywithmanymolecularfaces AT malgorzatamatuszczyk inflammatoryboweldiseaseoneentitywithmanymolecularfaces AT magdalenaosuch inflammatoryboweldiseaseoneentitywithmanymolecularfaces AT monikameglicka inflammatoryboweldiseaseoneentitywithmanymolecularfaces AT edytaszymanska inflammatoryboweldiseaseoneentitywithmanymolecularfaces AT joannabierła inflammatoryboweldiseaseoneentitywithmanymolecularfaces AT jaroslawkierkus inflammatoryboweldiseaseoneentitywithmanymolecularfaces |