Complement and coagulation cascade cross-talk in endometriosis and the potential of Janus Kinase inhibitors—a network meta-analysis

Complement and coagulation cascade cross-talk in endometriosis and the potential of Janus Kinase inhibitors—a network meta-analysis

BackgroundMolecular events that drive endometriosis (EM) and cause accompanying immune deregulation remain elusive. Our purpose was to identify key pathways involved in lesion formation across diverse populations and to detect transcriptomic changes in eutopic endometrium that accompany EM.MethodsWe...

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Main Authors: Monika Golinska, Aleksander Rycerz, Matylda Sobczak, Jedrzej Chrzanowski, Konrad Stawiski, Wojciech Fendler
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
endometriosis
eutopic and ectopic endometrium
network meta-analysis
complement and coagulation
mast cells
Janus kinase (JAK) inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1619434/full
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