Forecast successful prevention of infectious complications in preterm infants

The objective was to develop mathematical and statistical models forecast the success of prevention of infectious genesis of complications in premature infants with very low birth weight during the inpatient nursing care when used in programs of the therapy probiotic form based on Enterococcus faeci...

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Main Authors: N. V. Gonchar, L. A. Lo Schiavo, A. N. Suvorov, S. G. Grigoriev
Format: Article
Language:Russian
Published: Journal Infectology 2016-04-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/459
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author N. V. Gonchar
L. A. Lo Schiavo
A. N. Suvorov
S. G. Grigoriev
author_facet N. V. Gonchar
L. A. Lo Schiavo
A. N. Suvorov
S. G. Grigoriev
author_sort N. V. Gonchar
collection DOAJ
description The objective was to develop mathematical and statistical models forecast the success of prevention of infectious genesis of complications in premature infants with very low birth weight during the inpatient nursing care when used in programs of the therapy probiotic form based on Enterococcus faecium L3. We proposed the mathematical discriminant model forecast the success of prevention of infectious complications based on observations of 55 premature infants with very low birth weight in the second stage of nursing in a specialized department of pathology of newborn hospital and analysis of outcomes for the formation of infectious complicationsin 51 children. This model is based on the following six symptoms: 1) burdened obstetric and gynecological history mother; 2) the presence of chronic intoxication with the mother; 3) delivery is by caesarean section; 4) of the number of E. coli in the feces of children in real time polymerase chain reaction (relative to the norm values); 5) eosinophilia in the clinical analysis of blood; 6) use as a supplement to the diet of children probiotic liquid form on the basis of E. faecium L3. This model has a sufficiently high information capacity (80.4%) and statistically significant (p<0,01) for the prediction of the success of the prevention of infectious complications in premature infants with very low birth weight.
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series Журнал инфектологии
spelling doaj-art-ea3d50b1405d49e1bc497b99209447ab2025-08-20T04:00:15ZrusJournal InfectologyЖурнал инфектологии2072-67322016-04-01813237456Forecast successful prevention of infectious complications in preterm infantsN. V. Gonchar0L. A. Lo Schiavo1A. N. Suvorov2S. G. Grigoriev3North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg, Russia Scientice Research Institute of Children’s Infections, Saint-Petersburg, RussiaChildren’s City Hospital № 1, Saint-Petersburg, RussiaInstitute of Experimental Medicine, Saint-Petersburg, Russia Saint-Petersburg State University, Saint-Petersburg, RussiaScientice Research Institute of Children’s Infections, Saint-Petersburg, Russia Military-Medical Academy named after S.M. Kirov, Saint-Petersburg, RussiaThe objective was to develop mathematical and statistical models forecast the success of prevention of infectious genesis of complications in premature infants with very low birth weight during the inpatient nursing care when used in programs of the therapy probiotic form based on Enterococcus faecium L3. We proposed the mathematical discriminant model forecast the success of prevention of infectious complications based on observations of 55 premature infants with very low birth weight in the second stage of nursing in a specialized department of pathology of newborn hospital and analysis of outcomes for the formation of infectious complicationsin 51 children. This model is based on the following six symptoms: 1) burdened obstetric and gynecological history mother; 2) the presence of chronic intoxication with the mother; 3) delivery is by caesarean section; 4) of the number of E. coli in the feces of children in real time polymerase chain reaction (relative to the norm values); 5) eosinophilia in the clinical analysis of blood; 6) use as a supplement to the diet of children probiotic liquid form on the basis of E. faecium L3. This model has a sufficiently high information capacity (80.4%) and statistically significant (p<0,01) for the prediction of the success of the prevention of infectious complications in premature infants with very low birth weight.https://journal.niidi.ru/jofin/article/view/459preterm infantsthe discriminant modelinfectious complicationsthe probiotic strain enterococcus
spellingShingle N. V. Gonchar
L. A. Lo Schiavo
A. N. Suvorov
S. G. Grigoriev
Forecast successful prevention of infectious complications in preterm infants
Журнал инфектологии
preterm infants
the discriminant model
infectious complications
the probiotic strain enterococcus
title Forecast successful prevention of infectious complications in preterm infants
title_full Forecast successful prevention of infectious complications in preterm infants
title_fullStr Forecast successful prevention of infectious complications in preterm infants
title_full_unstemmed Forecast successful prevention of infectious complications in preterm infants
title_short Forecast successful prevention of infectious complications in preterm infants
title_sort forecast successful prevention of infectious complications in preterm infants
topic preterm infants
the discriminant model
infectious complications
the probiotic strain enterococcus
url https://journal.niidi.ru/jofin/article/view/459
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AT laloschiavo forecastsuccessfulpreventionofinfectiouscomplicationsinpreterminfants
AT ansuvorov forecastsuccessfulpreventionofinfectiouscomplicationsinpreterminfants
AT sggrigoriev forecastsuccessfulpreventionofinfectiouscomplicationsinpreterminfants