Association between type III collagen degradation and local tissue damage of a single joint

Association between type III collagen degradation and local tissue damage of a single joint

Objective: The development of disease-modifying drugs is limited by OA's heterogeneity and the challenge of defining clinical endpoints. Serological biomarkers are considered potential surrogate endpoints, but their contribution from single joints to systemic levels in OA patients is unclear. I...

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Bibliographic Details
Main Authors: Christian S. Thudium, Sten Rasmussen, Morten A. Karsdal, Anne-Christine Bay-Jensen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Biomarkers
ECM
Revision surgery
Collagen
Joint replacement
Osteoarthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913124000943
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