Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center
Purpose The goal of this cross-sectional study was to investigate the prevalence of vitamin D deficiency in young orthopedic trauma patients and its impact on bone mineral density (BMD) measured through computed tomography imaging of the lumbar spine. Methods Conducted at a level I trauma center, th...
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Korean Society of Traumatology
2024-12-01
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| Series: | Journal of Trauma and Injury |
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| Online Access: | http://jtraumainj.org/upload/pdf/jti-2024-0038.pdf |
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| author | Michael Booth Kenneth Sabacinski Colleen Watkins Erin Butcho Emilie Kramer Lukas Meadows Michelle A. Bramer |
| author_facet | Michael Booth Kenneth Sabacinski Colleen Watkins Erin Butcho Emilie Kramer Lukas Meadows Michelle A. Bramer |
| author_sort | Michael Booth |
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| description | Purpose The goal of this cross-sectional study was to investigate the prevalence of vitamin D deficiency in young orthopedic trauma patients and its impact on bone mineral density (BMD) measured through computed tomography imaging of the lumbar spine. Methods Conducted at a level I trauma center, this prospective cross-sectional analysis included 100 patients aged 18 to 50 years with non-fragility fractures. Vitamin D levels and Hounsfield units of the lumbar spine were recorded from computed tomography scans. Exclusion criteria included fragility fractures, lumbar surgery history, or lumbar bony/metastatic lesions. The correlation between vitamin D levels and BMD was assessed; vitamin D deficiency was defined as below 30 ng/mL. Results Among the participants, 75% were vitamin D–deficient, with an average vitamin D level of 25.0 ng/mL. No patients had osteoporosis based on Hounsfield units; however, 5% of patients were in the osteopenic range. In patients with normal vitamin D levels, there was an inverse correlation between vitamin D levels and BMD measured by Hounsfield units (P=0.025). Higher lumbar spine Hounsfield unit measurements correlated with lower vitamin D levels in this nondeficient population. Conclusions This study highlights a high prevalence of vitamin D deficiency in young orthopedic trauma patients, and it suggests a potential inverse relationship with BMD in patients with vitamin D levels >30 ng/mL. The absence of osteoporosis in our population raises questions about the influence of vitamin D on BMD in this young trauma patient demographic. Future research should explore the impact of vitamin D replacement on fracture union and investigate the interaction between vitamin D levels and bone health in the younger orthopedic trauma population. |
| format | Article |
| id | doaj-art-ea129a79833f49e0a9e94ed6fbdc1e12 |
| institution | Kabale University |
| issn | 2799-4317 2287-1683 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Korean Society of Traumatology |
| record_format | Article |
| series | Journal of Trauma and Injury |
| spelling | doaj-art-ea129a79833f49e0a9e94ed6fbdc1e122025-01-16T06:10:34ZengKorean Society of TraumatologyJournal of Trauma and Injury2799-43172287-16832024-12-0137427628010.20408/jti.2024.00381335Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma centerMichael Booth0Kenneth Sabacinski1Colleen Watkins2Erin Butcho3Emilie Kramer4Lukas Meadows5Michelle A. Bramer6 Department of Orthopaedics, West Virginia University, Morgantown, WV, USA Department of Orthopaedics, West Virginia University, Morgantown, WV, USA Department of Orthopaedics, West Virginia University, Morgantown, WV, USA Department of Neuroradiology, West Virginia University, Morgantown, WV, USA Department of Orthopaedics, West Virginia University, Morgantown, WV, USA Department of Radiology, West Virginia University, Morgantown, WV, USA Department of Orthopaedics, West Virginia University, Morgantown, WV, USAPurpose The goal of this cross-sectional study was to investigate the prevalence of vitamin D deficiency in young orthopedic trauma patients and its impact on bone mineral density (BMD) measured through computed tomography imaging of the lumbar spine. Methods Conducted at a level I trauma center, this prospective cross-sectional analysis included 100 patients aged 18 to 50 years with non-fragility fractures. Vitamin D levels and Hounsfield units of the lumbar spine were recorded from computed tomography scans. Exclusion criteria included fragility fractures, lumbar surgery history, or lumbar bony/metastatic lesions. The correlation between vitamin D levels and BMD was assessed; vitamin D deficiency was defined as below 30 ng/mL. Results Among the participants, 75% were vitamin D–deficient, with an average vitamin D level of 25.0 ng/mL. No patients had osteoporosis based on Hounsfield units; however, 5% of patients were in the osteopenic range. In patients with normal vitamin D levels, there was an inverse correlation between vitamin D levels and BMD measured by Hounsfield units (P=0.025). Higher lumbar spine Hounsfield unit measurements correlated with lower vitamin D levels in this nondeficient population. Conclusions This study highlights a high prevalence of vitamin D deficiency in young orthopedic trauma patients, and it suggests a potential inverse relationship with BMD in patients with vitamin D levels >30 ng/mL. The absence of osteoporosis in our population raises questions about the influence of vitamin D on BMD in this young trauma patient demographic. Future research should explore the impact of vitamin D replacement on fracture union and investigate the interaction between vitamin D levels and bone health in the younger orthopedic trauma population.http://jtraumainj.org/upload/pdf/jti-2024-0038.pdforthopedic traumavitamin dbone density |
| spellingShingle | Michael Booth Kenneth Sabacinski Colleen Watkins Erin Butcho Emilie Kramer Lukas Meadows Michelle A. Bramer Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center Journal of Trauma and Injury orthopedic trauma vitamin d bone density |
| title | Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center |
| title_full | Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center |
| title_fullStr | Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center |
| title_full_unstemmed | Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center |
| title_short | Vitamin D levels and bone mineral density: a prospective cross-sectional analysis of young orthopedic trauma patients at a rural United States trauma center |
| title_sort | vitamin d levels and bone mineral density a prospective cross sectional analysis of young orthopedic trauma patients at a rural united states trauma center |
| topic | orthopedic trauma vitamin d bone density |
| url | http://jtraumainj.org/upload/pdf/jti-2024-0038.pdf |
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