Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review
Introduction Scientific progress and translation of evidence into practice is impeded by poorly described interventions. The Template for Intervention Description and Replication (TIDieR) was developed to specify the minimal intervention elements that should be reported.Objectives (1) To assess the...
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BMJ Publishing Group
2019-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/9/12/e025511.full |
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| author | Marie Johnston Claire Scott Neil Scott M De Bruin Margaret Watson Mícheál de Barra Catriona Matheson Christine Bond |
| author_facet | Marie Johnston Claire Scott Neil Scott M De Bruin Margaret Watson Mícheál de Barra Catriona Matheson Christine Bond |
| author_sort | Marie Johnston |
| collection | DOAJ |
| description | Introduction Scientific progress and translation of evidence into practice is impeded by poorly described interventions. The Template for Intervention Description and Replication (TIDieR) was developed to specify the minimal intervention elements that should be reported.Objectives (1) To assess the extent to which outpatient pharmacy interventions were adequately reported. (2) To examine the dimension(s) across which reporting quality varies. (3) To examine trial characteristics that predict better reporting.Methods The sample comprised 86 randomised controlled trials identified in a Cochrane review of the effectiveness of pharmacist interventions on patient health outcomes. Duplicate, independent application of a modified 15-item TIDieR checklist was undertaken to assess the intervention reporting. The reporting/non-reporting of TIDieR items was analysed with principal component analysis to evaluate the dimensionality of reporting quality and regression analyses to assess predictors of reporting qualityResults In total, 422 (40%) TIDieR items were fully reported, 395 (38%) were partially reported and 231 (22%) were not reported. A further 242 items were deemed not applicable to the specific trials. Reporting quality loaded on one component which accounted for 26% of the variance in TIDieR scores. More recent trials reported a slightly greater number of TIDieR items (0.07 (95% CI 0.02 to 0.13) additional TIDieR items per year of publication). Trials reported an 0.09 (95% CI 0.04 to 0.14) additional TIDieR items per unit increase in impact factor (IF) of the journal in which the main report was published.Conclusions Most trials lacked adequate intervention reporting. This diminished the applied and scientific value of their research. The standard of intervention reporting is, however, gradually increasing and appears somewhat better in journals with higher IFs. The use of the TIDieR checklist to improve reporting could enhance the utility and replicability of trials, and reduce research waste. |
| format | Article |
| id | doaj-art-ea100b262a8c49bb9ac49bcd4c2ce12e |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2019-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-ea100b262a8c49bb9ac49bcd4c2ce12e2024-12-02T21:40:07ZengBMJ Publishing GroupBMJ Open2044-60552019-12-0191210.1136/bmjopen-2018-025511Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic reviewMarie Johnston0Claire Scott1Neil Scott2M De Bruin3Margaret Watson4Mícheál de Barra5Catriona Matheson6Christine Bond7Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UKThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UKThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UKRadboud University Medical Center, Radboud Institute for Health Sciences, Radboud, The NetherlandsThe Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UKLife Sciences, Brunel University London, Middlesex, UKUniversity of Stirling, Stirling, UKSchool of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UKIntroduction Scientific progress and translation of evidence into practice is impeded by poorly described interventions. The Template for Intervention Description and Replication (TIDieR) was developed to specify the minimal intervention elements that should be reported.Objectives (1) To assess the extent to which outpatient pharmacy interventions were adequately reported. (2) To examine the dimension(s) across which reporting quality varies. (3) To examine trial characteristics that predict better reporting.Methods The sample comprised 86 randomised controlled trials identified in a Cochrane review of the effectiveness of pharmacist interventions on patient health outcomes. Duplicate, independent application of a modified 15-item TIDieR checklist was undertaken to assess the intervention reporting. The reporting/non-reporting of TIDieR items was analysed with principal component analysis to evaluate the dimensionality of reporting quality and regression analyses to assess predictors of reporting qualityResults In total, 422 (40%) TIDieR items were fully reported, 395 (38%) were partially reported and 231 (22%) were not reported. A further 242 items were deemed not applicable to the specific trials. Reporting quality loaded on one component which accounted for 26% of the variance in TIDieR scores. More recent trials reported a slightly greater number of TIDieR items (0.07 (95% CI 0.02 to 0.13) additional TIDieR items per year of publication). Trials reported an 0.09 (95% CI 0.04 to 0.14) additional TIDieR items per unit increase in impact factor (IF) of the journal in which the main report was published.Conclusions Most trials lacked adequate intervention reporting. This diminished the applied and scientific value of their research. The standard of intervention reporting is, however, gradually increasing and appears somewhat better in journals with higher IFs. The use of the TIDieR checklist to improve reporting could enhance the utility and replicability of trials, and reduce research waste.https://bmjopen.bmj.com/content/9/12/e025511.full |
| spellingShingle | Marie Johnston Claire Scott Neil Scott M De Bruin Margaret Watson Mícheál de Barra Catriona Matheson Christine Bond Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review BMJ Open |
| title | Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review |
| title_full | Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review |
| title_fullStr | Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review |
| title_full_unstemmed | Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review |
| title_short | Do pharmacy intervention reports adequately describe their interventions? A template for intervention description and replication analysis of reports included in a systematic review |
| title_sort | do pharmacy intervention reports adequately describe their interventions a template for intervention description and replication analysis of reports included in a systematic review |
| url | https://bmjopen.bmj.com/content/9/12/e025511.full |
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