Case Report: Uncommon presentation of Ewing sarcoma complicated by hemophagocytic lymphohistiocytosis: a diagnostic dilemma and therapeutic challenge

Case Report: Uncommon presentation of Ewing sarcoma complicated by hemophagocytic lymphohistiocytosis: a diagnostic dilemma and therapeutic challenge

Hemophagocytic lymphohistiocytosis (HLH), also referred to as hemophagocytic syndrome (HPS), is a life-threatening condition characterized by excessive immune activation. It is commonly associated with genetic mutations, infections, autoimmune diseases, and malignancies. Malignancy-associated HLH (M...

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Bibliographic Details
Main Authors:	Zhuan Zou, Bin Chen, Fajuan Tang, Xihong Li, Chengshuang Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Oncology
Subjects:	hemophagocytic lymphohistiocytosis extraosseous ewing sarcoma case report Epstein-Barr virus (EBV) malignancy-associated HLH
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1613906/full
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