Sensitivity to an inhibitor of translation elongation in solid and hematologic cancers
Abstract Inhibitors of protein synthesis hold promise for cancer therapy because many cancer driver proteins are unstable and blocking synthesis leads to their depletion. We described previously SVC112, a small molecule inhibitor of translation elongation that inactivates Head and Neck Squamous Cell...
Saved in:
| Main Authors: | Nathan Gomes, Barbara Frederick, John Tentler, Tin Tin Su |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-06273-6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation
by: Andrea Grund, et al.
Published: (2019-08-01) -
Translation elongation: measurements and applications
by: Leslie Watkins, et al.
Published: (2025-12-01) -
ELOE: A WEB APPLICATION FOR ESTIMATION OF GENE TRANSLATION ELONGATION EFFICIENCY
by: V. S. Sokolov, et al.
Published: (2015-01-01) -
Elongation factor-P at the crossroads of the host-endosymbiont interface
by: Andrei Rajkovic, et al.
Published: (2015-09-01) -
Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation
by: Cristina Pop, et al.
Published: (2014-12-01)