CREATING A PROLONGED FORM OF ACETYLSALICYLIC ACID: AN EXPERIMENTAL APPROACH

CREATING A PROLONGED FORM OF ACETYLSALICYLIC ACID: AN EXPERIMENTAL APPROACH

Aim. The development of a prolonged form of acetylsalicylic acid (ASA) encapsulated into polymeric highly porous microcarriers using supercritical carbon dioxide and the subsequent study of ASA release kinetics in vitro and in vivo using high-performance liquid chromatographic (HPLC).Materials and m...

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Bibliographic Details
Main Authors: V. I. Sevastianov, V. K. Popov, V. Yu. Belov, S. V. Kursakov, E. N. Antonov, S. E. Bogorodsky
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2016-04-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
highly porous polymeric microparticles
polyethers
encapsulation
acetylsalicylic acid
supercritical dioxide
release kinetics
blood plasma
hplc
Online Access:https://journal.transpl.ru/vtio/article/view/615
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