Increase in body weight is lowered when mice received fecal microbiota transfer from donor mice treated with the AT1 receptor antagonist telmisartan

Increase in body weight is lowered when mice received fecal microbiota transfer from donor mice treated with the AT1 receptor antagonist telmisartan

IntroductionTreatment of rodents with the AT1 blocker (ARB) telmisartan (TEL) has an anti-adipose effect. Among other mechanisms, we also have attributed the anti-adipose action to diet-independent alterations in gut microbiota. Thus, we aimed here to confirm this mechanism by using the fecal microb...

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Bibliographic Details
Main Authors: Marco L. Freschi, Axel Künstner, Gianna Huber, Ines Stölting, Hauke Busch, Misa Hirose, Walter Raasch
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
obesity
renin-angiotensin aldosterone system (RAAS)
telmisartan
microbiota transfer
desulovibrio
weight reduction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1453989/full
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