Antibiotic pollution and associated antimicrobial resistance in the environment
The widespread and injudicious usage of antibiotics to contain pathogenic microbial infections, coupled with inadequate treatment of wastes containing non-metabolized antibiotics and their residues is resulting in rising environmental antibiotic concentrations, leading to ‘antibiotic pollution’. Ant...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-11-01
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| Series: | Journal of Hazardous Materials Letters |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666911024000042 |
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| author | Pramod Barathe Kawaljeet Kaur Sagar Reddy Varsha Shriram Vinay Kumar |
| author_facet | Pramod Barathe Kawaljeet Kaur Sagar Reddy Varsha Shriram Vinay Kumar |
| author_sort | Pramod Barathe |
| collection | DOAJ |
| description | The widespread and injudicious usage of antibiotics to contain pathogenic microbial infections, coupled with inadequate treatment of wastes containing non-metabolized antibiotics and their residues is resulting in rising environmental antibiotic concentrations, leading to ‘antibiotic pollution’. Antibiotic pollution is an emerging global challenge as it is proving a major driver for antibiotic- or antimicrobial-resistance (ABR/ AMR) with escalating ramifications worldwide, precipitating a surge in human morbidity. The extensive administration of antibiotics across domains such as human healthcare settings, agriculture, and aquaculture farming endangers the presence of antibiotics in diverse matrices including water, soil, and air. As a result, this dissemination significantly leads to the development of antibiotic resistance in the profuse sectors of the environment further provoking consequential health implications at different trophic levels. Owing to its significance, and to mitigate antibiotic pollution and its subsequential AMR, governmental guidelines and regulations are implemented across the globe to cultivate public awareness as concerted efforts for addressing this global predicament. Given the insufficient attention to the growing antibiotic pollution issues, prompt efforts must be taken to contemplate current circumstances and the rigor of the ongoing research. In this review, we endeavor to elucidate the escalation of antibiotic concentration and antibiotic-driven AMR in water, air, and soil environments with potential public health threats. Further, it focuses on various strategies and interventions to attenuate antibiotic pollution and mitigate its adverse impacts on the healthcare infrastructure, highlighting the success stories, challenges, and future directions. |
| format | Article |
| id | doaj-art-e9570637c9be45e08ed32e8726f0aa5b |
| institution | Kabale University |
| issn | 2666-9110 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Hazardous Materials Letters |
| spelling | doaj-art-e9570637c9be45e08ed32e8726f0aa5b2024-11-22T07:39:27ZengElsevierJournal of Hazardous Materials Letters2666-91102024-11-015100105Antibiotic pollution and associated antimicrobial resistance in the environmentPramod Barathe0Kawaljeet Kaur1Sagar Reddy2Varsha Shriram3Vinay Kumar4Department of Biotechnology, Modern College of Arts, Science and Commerce, Savitribai Phule Pune University, Ganeshkhind, Pune, Maharashtra 411016, IndiaDepartment of Biotechnology, Modern College of Arts, Science and Commerce, Savitribai Phule Pune University, Ganeshkhind, Pune, Maharashtra 411016, IndiaDepartment of Biotechnology, Modern College of Arts, Science and Commerce, Savitribai Phule Pune University, Ganeshkhind, Pune, Maharashtra 411016, India; Department of Botany, Prof. Ramkrishna More College, Savitribai Phule Pune University, Akurdi, Pune, Maharashtra 411016, IndiaDepartment of Botany, Prof. Ramkrishna More College, Savitribai Phule Pune University, Akurdi, Pune, Maharashtra 411016, IndiaDepartment of Biotechnology, Modern College of Arts, Science and Commerce, Savitribai Phule Pune University, Ganeshkhind, Pune, Maharashtra 411016, India; Corresponding author.The widespread and injudicious usage of antibiotics to contain pathogenic microbial infections, coupled with inadequate treatment of wastes containing non-metabolized antibiotics and their residues is resulting in rising environmental antibiotic concentrations, leading to ‘antibiotic pollution’. Antibiotic pollution is an emerging global challenge as it is proving a major driver for antibiotic- or antimicrobial-resistance (ABR/ AMR) with escalating ramifications worldwide, precipitating a surge in human morbidity. The extensive administration of antibiotics across domains such as human healthcare settings, agriculture, and aquaculture farming endangers the presence of antibiotics in diverse matrices including water, soil, and air. As a result, this dissemination significantly leads to the development of antibiotic resistance in the profuse sectors of the environment further provoking consequential health implications at different trophic levels. Owing to its significance, and to mitigate antibiotic pollution and its subsequential AMR, governmental guidelines and regulations are implemented across the globe to cultivate public awareness as concerted efforts for addressing this global predicament. Given the insufficient attention to the growing antibiotic pollution issues, prompt efforts must be taken to contemplate current circumstances and the rigor of the ongoing research. In this review, we endeavor to elucidate the escalation of antibiotic concentration and antibiotic-driven AMR in water, air, and soil environments with potential public health threats. Further, it focuses on various strategies and interventions to attenuate antibiotic pollution and mitigate its adverse impacts on the healthcare infrastructure, highlighting the success stories, challenges, and future directions.http://www.sciencedirect.com/science/article/pii/S2666911024000042AntibioticsAntibiotic pollutionAntibiotic resistanceAntimicrobial resistanceAntibiotic consumptionAntibiotic waste treatment |
| spellingShingle | Pramod Barathe Kawaljeet Kaur Sagar Reddy Varsha Shriram Vinay Kumar Antibiotic pollution and associated antimicrobial resistance in the environment Journal of Hazardous Materials Letters Antibiotics Antibiotic pollution Antibiotic resistance Antimicrobial resistance Antibiotic consumption Antibiotic waste treatment |
| title | Antibiotic pollution and associated antimicrobial resistance in the environment |
| title_full | Antibiotic pollution and associated antimicrobial resistance in the environment |
| title_fullStr | Antibiotic pollution and associated antimicrobial resistance in the environment |
| title_full_unstemmed | Antibiotic pollution and associated antimicrobial resistance in the environment |
| title_short | Antibiotic pollution and associated antimicrobial resistance in the environment |
| title_sort | antibiotic pollution and associated antimicrobial resistance in the environment |
| topic | Antibiotics Antibiotic pollution Antibiotic resistance Antimicrobial resistance Antibiotic consumption Antibiotic waste treatment |
| url | http://www.sciencedirect.com/science/article/pii/S2666911024000042 |
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