Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy
Abstract Objectives Compare the differences in perioperative clinical characteristics of lung cancer patients of different genders who have undergone VATS lobectomy, and explore the impact of these differences on the short-term prognosis of patients. Methods A total of 338 consecutive patients with...
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BMC
2024-12-01
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| Series: | Journal of Cardiothoracic Surgery |
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| Online Access: | https://doi.org/10.1186/s13019-024-03211-x |
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| author | Wei Chen Qiangqiang Zheng Yi Shen Min Liang Yang Yuan Yusong Lu Yunfeng Zhou |
| author_facet | Wei Chen Qiangqiang Zheng Yi Shen Min Liang Yang Yuan Yusong Lu Yunfeng Zhou |
| author_sort | Wei Chen |
| collection | DOAJ |
| description | Abstract Objectives Compare the differences in perioperative clinical characteristics of lung cancer patients of different genders who have undergone VATS lobectomy, and explore the impact of these differences on the short-term prognosis of patients. Methods A total of 338 consecutive patients with lung cancer who underwent VATS lobectomy in our hospital from August 2021 to August 2022 were retrospectively analyzed, they were divided into male group and female group. The perioperative characteristics and short-term prognosis of different groups were compared. The multivariate binary logistic regression analysis was used to analyze the risk factors. Results There were statistically significant differences between male and female patients in age of onset, body surface area (BSA), smoking rate, alcohol consumption rate, hypertension incidence, pulmonary function and clinical stage. There were statistically significant differences between male and female patients in operation time and lymph node dissection. The probability of postoperative complications, such as pulmonary infection, persistent air leakage and severe subcutaneous emphysema, in male patients was significantly higher than that in female patients. The average daily postoperative thoracic drainage volume in male patients was considerably higher than that in female patients, and the postoperative duration of thoracic drainage tube and hospital stay in male patients were significantly longer than those in female patients. After multiple regression analysis, low FEVI values in males was found to be an independent risk factor for postoperative complications. Conclusions Compared with female patients, male patients with lung cancer are more likely to have unfavorable factors such as older age, higher smoking rate, poor pulmonary function and late clinical stage of tumors when they undergoing VATS surgery treatment. The appropriate thoracic drainage time can be selected according to gender differences to shorten the length of hospital stay. The incidence of postoperative complications is higher in male patients, especially those with poor pulmonary function, and active perioperative intervention is required to reduce the incidence of postoperative complications. |
| format | Article |
| id | doaj-art-e9170ccca2cc4d59bff251bbdfdcb739 |
| institution | Kabale University |
| issn | 1749-8090 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj-art-e9170ccca2cc4d59bff251bbdfdcb7392025-01-05T12:45:47ZengBMCJournal of Cardiothoracic Surgery1749-80902024-12-0119111110.1186/s13019-024-03211-xRelationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomyWei Chen0Qiangqiang Zheng1Yi Shen2Min Liang3Yang Yuan4Yusong Lu5Yunfeng Zhou6Department of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityDepartment of Thoracic Surgery, West China School of Public Health and West China Fourth Hospital, Sichuan UniversityAbstract Objectives Compare the differences in perioperative clinical characteristics of lung cancer patients of different genders who have undergone VATS lobectomy, and explore the impact of these differences on the short-term prognosis of patients. Methods A total of 338 consecutive patients with lung cancer who underwent VATS lobectomy in our hospital from August 2021 to August 2022 were retrospectively analyzed, they were divided into male group and female group. The perioperative characteristics and short-term prognosis of different groups were compared. The multivariate binary logistic regression analysis was used to analyze the risk factors. Results There were statistically significant differences between male and female patients in age of onset, body surface area (BSA), smoking rate, alcohol consumption rate, hypertension incidence, pulmonary function and clinical stage. There were statistically significant differences between male and female patients in operation time and lymph node dissection. The probability of postoperative complications, such as pulmonary infection, persistent air leakage and severe subcutaneous emphysema, in male patients was significantly higher than that in female patients. The average daily postoperative thoracic drainage volume in male patients was considerably higher than that in female patients, and the postoperative duration of thoracic drainage tube and hospital stay in male patients were significantly longer than those in female patients. After multiple regression analysis, low FEVI values in males was found to be an independent risk factor for postoperative complications. Conclusions Compared with female patients, male patients with lung cancer are more likely to have unfavorable factors such as older age, higher smoking rate, poor pulmonary function and late clinical stage of tumors when they undergoing VATS surgery treatment. The appropriate thoracic drainage time can be selected according to gender differences to shorten the length of hospital stay. The incidence of postoperative complications is higher in male patients, especially those with poor pulmonary function, and active perioperative intervention is required to reduce the incidence of postoperative complications.https://doi.org/10.1186/s13019-024-03211-xLung cancerGender differenceLobectomyPerioperative period |
| spellingShingle | Wei Chen Qiangqiang Zheng Yi Shen Min Liang Yang Yuan Yusong Lu Yunfeng Zhou Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy Journal of Cardiothoracic Surgery Lung cancer Gender difference Lobectomy Perioperative period |
| title | Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy |
| title_full | Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy |
| title_fullStr | Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy |
| title_full_unstemmed | Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy |
| title_short | Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy |
| title_sort | relationship between gender and perioperative clinical features in lung cancer patients who underwent vats lobectomy |
| topic | Lung cancer Gender difference Lobectomy Perioperative period |
| url | https://doi.org/10.1186/s13019-024-03211-x |
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