Characterization of double-negative T cells in colorectal cancers and their corresponding lymph nodes

Characterization of double-negative T cells in colorectal cancers and their corresponding lymph nodes

TCRαβ+ CD4− CD8− double-negative T (DNT) cells are minor populations in peripheral blood, and their roles have mostly been discussed in inflammation and autoimmunity. However, the functions of DNT cells in tumor microenvironment remain to be elucidated. We investigated their characteristics, possibl...

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Bibliographic Details
Main Authors: Kazumi Okamura, Lifang Wang, Satoshi Nagayama, Makiko Yamashita, Tomohiro Tate, Saki Matsumoto, Manabu Takamatsu, Shigehisa Kitano, Kazuma Kiyotani, Yusuke Nakamura
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
CD8+ T cells
colorectal cancer
double-negative T cells
granzyme K
T cell receptor
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2024.2373530
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