Case report: The case of T-cell acute lymphoblastic leukemia treated with chemotherapy followed by anti-CD7 CAR-T cells using retroviral vector

Case report: The case of T-cell acute lymphoblastic leukemia treated with chemotherapy followed by anti-CD7 CAR-T cells using retroviral vector

CD7-targeted chimeric antigen receptor-T (CAR-T) cell therapy has shown great promise in the treatment of relapsed/refractory T-cell acute lymphoblastic leukemia (T-ALL). In this study, we reported a case of a 34-year-old male patient with T-ALL who finally developed multi-line drug resistance and r...

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Bibliographic Details
Main Authors: Huanhuan Zhou, Wenxiang Zhu, Qihong Ma, Ning Liu, Mengdi Jin, Yaru Feng, Lijun Zhao, Rui Sun, Rongyou Li, Huaxiu Li, Yuanyuan Shi, Jianxun Wang, Liqiong Liu, Zhi Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
T-ALL
CD7 CAR-T
chemotherapy
retroviral vectors
complete remission
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1519055/full
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