Blood serum levels of E-cadherin in patients with colorectal cancer
Introduction : Colorectal cancer is the second most common cancer in terms of incidence in Poland. It is also the second most common cause of cancer deaths in men and the third women. In 75–80% of cases, depending on sources, it is of an occasional nature, and in the remaining 20–25% it has a heredi...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2017-09-01
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| Series: | Gastroenterology Review |
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| Online Access: | https://www.termedia.pl/Blood-serum-levels-of-E-cadherin-in-patients-with-colorectal-cancer,41,30727,1,1.html |
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| author | Dariusz Cepowicz Konrad Zaręba Anna Pryczynicz Tomasz Dawidziuk Joanna Żurawska Joanna Hołody-Zaręba Mariusz Gryko Bogusław Kędra |
| author_facet | Dariusz Cepowicz Konrad Zaręba Anna Pryczynicz Tomasz Dawidziuk Joanna Żurawska Joanna Hołody-Zaręba Mariusz Gryko Bogusław Kędra |
| author_sort | Dariusz Cepowicz |
| collection | DOAJ |
| description | Introduction : Colorectal cancer is the second most common cancer in terms of incidence in Poland. It is also the second most common cause of cancer deaths in men and the third women. In 75–80% of cases, depending on sources, it is of an occasional nature, and in the remaining 20–25% it has a hereditary character.
Aim : To compare the levels of E-cadherin in blood serum with some histopathological and clinical features. E-cadherin is an adhesion molecule, loss of function of which is suspected to influence both cancer progression and metastasis.
Material and methods : The study group comprised 48 patients diagnosed with colorectal cancer treated surgically in the Second Department of General and Gastroenterological Surgery, Medical University Hospital in Bialystok.
Results : As has been shown here, there is no statistically significant relationship between the levels of E-cadherin in blood serum and the possible prognosis to the progression of colorectal cancer. However, it was indicated that there appears to be a statistically significant relationship between blood serum E-cadherin levels and the levels of alanine aminotransferase and aspartate aminotransferase in patients with colorectal cancer.
Conclusions : The authors suggest that this significance may require further study. |
| format | Article |
| id | doaj-art-e8dbbab588ff4b048255a43213a7b67f |
| institution | Kabale University |
| issn | 1895-5770 1897-4317 |
| language | English |
| publishDate | 2017-09-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Gastroenterology Review |
| spelling | doaj-art-e8dbbab588ff4b048255a43213a7b67f2025-01-10T14:06:15ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172017-09-0112318619110.5114/pg.2017.7047130727Blood serum levels of E-cadherin in patients with colorectal cancerDariusz CepowiczKonrad ZarębaAnna PryczyniczTomasz DawidziukJoanna ŻurawskaJoanna Hołody-ZarębaMariusz GrykoBogusław KędraIntroduction : Colorectal cancer is the second most common cancer in terms of incidence in Poland. It is also the second most common cause of cancer deaths in men and the third women. In 75–80% of cases, depending on sources, it is of an occasional nature, and in the remaining 20–25% it has a hereditary character. Aim : To compare the levels of E-cadherin in blood serum with some histopathological and clinical features. E-cadherin is an adhesion molecule, loss of function of which is suspected to influence both cancer progression and metastasis. Material and methods : The study group comprised 48 patients diagnosed with colorectal cancer treated surgically in the Second Department of General and Gastroenterological Surgery, Medical University Hospital in Bialystok. Results : As has been shown here, there is no statistically significant relationship between the levels of E-cadherin in blood serum and the possible prognosis to the progression of colorectal cancer. However, it was indicated that there appears to be a statistically significant relationship between blood serum E-cadherin levels and the levels of alanine aminotransferase and aspartate aminotransferase in patients with colorectal cancer. Conclusions : The authors suggest that this significance may require further study.https://www.termedia.pl/Blood-serum-levels-of-E-cadherin-in-patients-with-colorectal-cancer,41,30727,1,1.htmlE-cadherin colon cancer colorectal cancer aspartate aminotransferase alanine aminotransferase |
| spellingShingle | Dariusz Cepowicz Konrad Zaręba Anna Pryczynicz Tomasz Dawidziuk Joanna Żurawska Joanna Hołody-Zaręba Mariusz Gryko Bogusław Kędra Blood serum levels of E-cadherin in patients with colorectal cancer Gastroenterology Review E-cadherin colon cancer colorectal cancer aspartate aminotransferase alanine aminotransferase |
| title | Blood serum levels of E-cadherin in patients with colorectal cancer |
| title_full | Blood serum levels of E-cadherin in patients with colorectal cancer |
| title_fullStr | Blood serum levels of E-cadherin in patients with colorectal cancer |
| title_full_unstemmed | Blood serum levels of E-cadherin in patients with colorectal cancer |
| title_short | Blood serum levels of E-cadherin in patients with colorectal cancer |
| title_sort | blood serum levels of e cadherin in patients with colorectal cancer |
| topic | E-cadherin colon cancer colorectal cancer aspartate aminotransferase alanine aminotransferase |
| url | https://www.termedia.pl/Blood-serum-levels-of-E-cadherin-in-patients-with-colorectal-cancer,41,30727,1,1.html |
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