UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS
<p>Follicular lymphoma (FL) remains incurable despite advances in new strategies of treatment, including monoclonal antibodies (MoAb). Except for early stages, FL is characterized by responses to treatments and systematic relapses. The main objective in this disease is to achieve a bet...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2012-01-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | http://www.mjhid.org/article/view/11091 |
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| _version_ | 1846143903145656320 |
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| author | Mónica Cabrero Alba Redondo Alejandro Martin Dolores Caballero |
| author_facet | Mónica Cabrero Alba Redondo Alejandro Martin Dolores Caballero |
| author_sort | Mónica Cabrero |
| collection | DOAJ |
| description | <p>Follicular lymphoma (FL) remains incurable despite advances in new strategies of treatment, including monoclonal antibodies (MoAb). Except for early stages, FL is characterized by responses to treatments and systematic relapses. The main objective in this disease is to achieve a better progression free survival (PFS) and to increase overall survival (OS), mainly in young patients. In order to improve the results of conventional chemotherapy, autologous stem cell transplant (ASCT) is a feasible treatment in these patients. In this moment, ASCT is not recommended as first line treatment, except for transformed FL, but is a good strategy as salvage therapy with an improved PFS and OS. New drugs have been introduced to enhance responses of ASCT, but nowadays they are not part of conventional conditioning regimen.</p> |
| format | Article |
| id | doaj-art-e8dafb9da4664d81a59725512bfdc2c0 |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-e8dafb9da4664d81a59725512bfdc2c02024-12-02T09:52:12ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062012-01-0141e2012074e2012074UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMASMónica CabreroAlba RedondoAlejandro MartinDolores Caballero<p>Follicular lymphoma (FL) remains incurable despite advances in new strategies of treatment, including monoclonal antibodies (MoAb). Except for early stages, FL is characterized by responses to treatments and systematic relapses. The main objective in this disease is to achieve a better progression free survival (PFS) and to increase overall survival (OS), mainly in young patients. In order to improve the results of conventional chemotherapy, autologous stem cell transplant (ASCT) is a feasible treatment in these patients. In this moment, ASCT is not recommended as first line treatment, except for transformed FL, but is a good strategy as salvage therapy with an improved PFS and OS. New drugs have been introduced to enhance responses of ASCT, but nowadays they are not part of conventional conditioning regimen.</p>http://www.mjhid.org/article/view/11091 |
| spellingShingle | Mónica Cabrero Alba Redondo Alejandro Martin Dolores Caballero UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS Mediterranean Journal of Hematology and Infectious Diseases |
| title | UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS |
| title_full | UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS |
| title_fullStr | UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS |
| title_full_unstemmed | UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS |
| title_short | UPDATE ON THE ROLE OF AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN FOLLICULAR LYMPHOMAS |
| title_sort | update on the role of autologous hematopoietic stem cell transplant in follicular lymphomas |
| url | http://www.mjhid.org/article/view/11091 |
| work_keys_str_mv | AT monicacabrero updateontheroleofautologoushematopoieticstemcelltransplantinfollicularlymphomas AT albaredondo updateontheroleofautologoushematopoieticstemcelltransplantinfollicularlymphomas AT alejandromartin updateontheroleofautologoushematopoieticstemcelltransplantinfollicularlymphomas AT dolorescaballero updateontheroleofautologoushematopoieticstemcelltransplantinfollicularlymphomas |