Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma
The current study describes the in-situ growth of ZnS/MoS2 on cellulose paper using the thin-film microextraction (TFME) method. On cellulose paper, ZnS/MoS2 was grown using a simple, easy, and inexpensive hydrothermal method. The digoxin was quantified after TFME using high-performance liquid chrom...
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| Format: | Article |
| Language: | English |
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Iranian Chemical Society
2024-01-01
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| Series: | Nanochemistry Research |
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| Online Access: | http://www.nanochemres.org/article_184836_366ab620b1380bdcb62b4f6d1956193c.pdf |
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| author | Marzieh Piryaei Mir Mahdi Abolghasemi Sodabeh Memari |
| author_facet | Marzieh Piryaei Mir Mahdi Abolghasemi Sodabeh Memari |
| author_sort | Marzieh Piryaei |
| collection | DOAJ |
| description | The current study describes the in-situ growth of ZnS/MoS2 on cellulose paper using the thin-film microextraction (TFME) method. On cellulose paper, ZnS/MoS2 was grown using a simple, easy, and inexpensive hydrothermal method. The digoxin was quantified after TFME using high-performance liquid chromatography-UV detection (HPLC-UV). The effect of effective parameters such as extraction time, extraction temperature, agitation speed, and sample ionic strength was investigated, and the best conditions were selected. Under ideal conditions, a calibration curve with good linearity (R2=0.987) and a low limit of detection (LOD) in the range of 0.01–100 ng mL-1 was obtained. The detection limits were 0.03 ng mL-1. For the digoxin, the relative standard deviations (RSDs) were 5.3%. The method was successfully applied to the study of urine and plasma. Relative recoveries were found to range between 96% and102 %. The proposed method provided a straightforward, efficient, and environmentally friendly way for determining digoxin in real-world samples. |
| format | Article |
| id | doaj-art-e8b5c179a38e41cd81f3369f84ee2f04 |
| institution | Kabale University |
| issn | 2538-4279 2423-818X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Iranian Chemical Society |
| record_format | Article |
| series | Nanochemistry Research |
| spelling | doaj-art-e8b5c179a38e41cd81f3369f84ee2f042025-01-12T10:25:03ZengIranian Chemical SocietyNanochemistry Research2538-42792423-818X2024-01-0191687610.22036/NCR.2024.01.08184836Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasmaMarzieh Piryaei0Mir Mahdi Abolghasemi1Sodabeh Memari2Department of Chemistry, Faculty of Science, University of Maragheh, Maragheh, IranDepartment of Chemistry, Faculty of Science, University of Maragheh, Maragheh, IranDepartment of Chemistry, Faculty of Science, University of Maragheh, Maragheh, IranThe current study describes the in-situ growth of ZnS/MoS2 on cellulose paper using the thin-film microextraction (TFME) method. On cellulose paper, ZnS/MoS2 was grown using a simple, easy, and inexpensive hydrothermal method. The digoxin was quantified after TFME using high-performance liquid chromatography-UV detection (HPLC-UV). The effect of effective parameters such as extraction time, extraction temperature, agitation speed, and sample ionic strength was investigated, and the best conditions were selected. Under ideal conditions, a calibration curve with good linearity (R2=0.987) and a low limit of detection (LOD) in the range of 0.01–100 ng mL-1 was obtained. The detection limits were 0.03 ng mL-1. For the digoxin, the relative standard deviations (RSDs) were 5.3%. The method was successfully applied to the study of urine and plasma. Relative recoveries were found to range between 96% and102 %. The proposed method provided a straightforward, efficient, and environmentally friendly way for determining digoxin in real-world samples.http://www.nanochemres.org/article_184836_366ab620b1380bdcb62b4f6d1956193c.pdfthin film microextractioncellulose paperznsmos2hplc |
| spellingShingle | Marzieh Piryaei Mir Mahdi Abolghasemi Sodabeh Memari Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma Nanochemistry Research thin film microextraction cellulose paper zns mos2 hplc |
| title | Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma |
| title_full | Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma |
| title_fullStr | Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma |
| title_full_unstemmed | Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma |
| title_short | Three-dimensional ZnS/MoS2 on cellulose paper for determination of Digoxin in urine and plasma |
| title_sort | three dimensional zns mos2 on cellulose paper for determination of digoxin in urine and plasma |
| topic | thin film microextraction cellulose paper zns mos2 hplc |
| url | http://www.nanochemres.org/article_184836_366ab620b1380bdcb62b4f6d1956193c.pdf |
| work_keys_str_mv | AT marziehpiryaei threedimensionalznsmos2oncellulosepaperfordeterminationofdigoxininurineandplasma AT mirmahdiabolghasemi threedimensionalznsmos2oncellulosepaperfordeterminationofdigoxininurineandplasma AT sodabehmemari threedimensionalznsmos2oncellulosepaperfordeterminationofdigoxininurineandplasma |