Burdock Fructooligosaccharide Protects Against Diabetic Nephropathy in Mice by Regulating Nrf2 Signaling

Burdock Fructooligosaccharide Protects Against Diabetic Nephropathy in Mice by Regulating Nrf2 Signaling

ABSTRACT Diabetic nephropathy (DN) is a common complication of diabetes mellitus, with oxidative stress playing a critical role in its development. Burdock fructooligosaccharide (BFO), a major compound in Burdock, exhibits antioxidative effects. However, its mechanisms of action and effects on diabe...

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Main Authors: Lei Zhu, Mengru Ding, Lina Liu, Pingchuan Yuan, Taili Shao, Chunyan Liu, Chuanhu Xi, Jun Han, Yuyan Zhou, Donglin Zhang, Guodong Wang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Pharmacology Research & Perspectives
Subjects:
apoptosis
diabetes mellitus
Nrf2/HO‐1 signaling
oxidative stress
polysaccharide
Online Access:https://doi.org/10.1002/prp2.70094
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