Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations.

Integrating EMR-linked and in vivo functional genetic data to identify new genotype-phenotype associations.

The coupling of electronic medical records (EMR) with genetic data has created the potential for implementing reverse genetic approaches in humans, whereby the function of a gene is inferred from the shared pattern of morbidity among homozygotes of a genetic variant. We explored the feasibility of t...

Full description

Saved in:
Bibliographic Details
Main Authors: Jonathan D Mosley, Sara L Van Driest, Peter E Weeke, Jessica T Delaney, Quinn S Wells, Lisa Bastarache, Dan M Roden, Josh C Denny
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0100322
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items