The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects
Purpose: The aim of this study was to determine the effects of 2% pilocarpine ophthalmic solution on the depth of field and the pupil size of human eye in the presbyopic population. Settings and Design: Prospective experimental study. Methods: The prospective study included 120 presbyopic people age...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.4103/IJO.IJO_130_24 |
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| author | Ashith Tripathi Sebin C Sebastian Himanshu Yadav Iqra Jamal Khan Vandana Kamath |
| author_facet | Ashith Tripathi Sebin C Sebastian Himanshu Yadav Iqra Jamal Khan Vandana Kamath |
| author_sort | Ashith Tripathi |
| collection | DOAJ |
| description | Purpose:
The aim of this study was to determine the effects of 2% pilocarpine ophthalmic solution on the depth of field and the pupil size of human eye in the presbyopic population.
Settings and Design:
Prospective experimental study.
Methods:
The prospective study included 120 presbyopic people aged between 40 and 55. All willing subjects underwent a comprehensive eye examination that included measuring the visual acuity for distance and near, retinoscopy, refraction, anterior and posterior segment examination, depth of field, and pupil size in room illumination. Following a preliminary examination, 2% pilocarpine ophthalmic solution was instilled in both eyes, and after various intervals of 15, 30, and 45 min, the depth of field and the pupil size were measured.
Results:
Before instillation of 2% pilocarpine solution, the mean pupil size was 0.34 mm with a standard deviation (SD) of ±0.37. After instillation, the mean pupil size changed to 2.20, 1.91, and 1.57 mm with SD of ±0.43, ±0.27, and ±0.34 mm, respectively, in 15, 30, and 45 min time intervals. Initial mean depth of field also changed from 1.76 D (SD ± 0.20) to 1.72, 1.65, and 1.59 D with SD of ±0.20, ±0.16, and ±0.22 D, respectively, in 15, 30, and 45 min time intervals.
Conclusion:
The study concludes that pupillary miotics create a pinhole effect after the instillation of 2% pilocarpine ophthalmic drop, extending the depth of field. The effect was highly clinically significant at 45 min with a P value <0.001. |
| format | Article |
| id | doaj-art-e87cbbfef6404be3b24ce328dfcaa1b3 |
| institution | Kabale University |
| issn | 0301-4738 1998-3689 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj-art-e87cbbfef6404be3b24ce328dfcaa1b32024-12-09T09:09:26ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892024-12-0172121795179710.4103/IJO.IJO_130_24The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjectsAshith TripathiSebin C SebastianHimanshu YadavIqra Jamal KhanVandana KamathPurpose: The aim of this study was to determine the effects of 2% pilocarpine ophthalmic solution on the depth of field and the pupil size of human eye in the presbyopic population. Settings and Design: Prospective experimental study. Methods: The prospective study included 120 presbyopic people aged between 40 and 55. All willing subjects underwent a comprehensive eye examination that included measuring the visual acuity for distance and near, retinoscopy, refraction, anterior and posterior segment examination, depth of field, and pupil size in room illumination. Following a preliminary examination, 2% pilocarpine ophthalmic solution was instilled in both eyes, and after various intervals of 15, 30, and 45 min, the depth of field and the pupil size were measured. Results: Before instillation of 2% pilocarpine solution, the mean pupil size was 0.34 mm with a standard deviation (SD) of ±0.37. After instillation, the mean pupil size changed to 2.20, 1.91, and 1.57 mm with SD of ±0.43, ±0.27, and ±0.34 mm, respectively, in 15, 30, and 45 min time intervals. Initial mean depth of field also changed from 1.76 D (SD ± 0.20) to 1.72, 1.65, and 1.59 D with SD of ±0.20, ±0.16, and ±0.22 D, respectively, in 15, 30, and 45 min time intervals. Conclusion: The study concludes that pupillary miotics create a pinhole effect after the instillation of 2% pilocarpine ophthalmic drop, extending the depth of field. The effect was highly clinically significant at 45 min with a P value <0.001.https://journals.lww.com/10.4103/IJO.IJO_130_24depth of fieldpilocarpinepresbyopiapupil size |
| spellingShingle | Ashith Tripathi Sebin C Sebastian Himanshu Yadav Iqra Jamal Khan Vandana Kamath The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects Indian Journal of Ophthalmology depth of field pilocarpine presbyopia pupil size |
| title | The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects |
| title_full | The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects |
| title_fullStr | The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects |
| title_full_unstemmed | The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects |
| title_short | The effect of 2% pilocarpine on depth of field in different time intervals among presbyopic subjects |
| title_sort | effect of 2 pilocarpine on depth of field in different time intervals among presbyopic subjects |
| topic | depth of field pilocarpine presbyopia pupil size |
| url | https://journals.lww.com/10.4103/IJO.IJO_130_24 |
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