Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl)
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 (furfuryl and furan derivatives with and without additional side‐chain substituents...
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Wiley
2023-03-01
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| Series: | EFSA Journal |
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| Online Access: | https://doi.org/10.2903/j.efsa.2023.7868 |
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| author | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Paul Brantom Andrew Chesson Johannes Westendorf Paola Manini Birgit Dusemund |
| author_facet | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Paul Brantom Andrew Chesson Johannes Westendorf Paola Manini Birgit Dusemund |
| author_sort | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) |
| collection | DOAJ |
| description | Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 (furfuryl and furan derivatives with and without additional side‐chain substituents and heteroatoms), when used as sensory additives (flavourings) in feed for all animal species. 2‐Acetylfuran [13.054] was tested in tolerance studies in chickens for fattening, weaned piglets and cattle for fattening. No adverse effects were observed in the tolerance studies at 10‐fold the intended use level. The FEEDAP Panel concluded that 2‐acetylfuran [13.054] is safe for these species at the proposed use level of 0.5 mg/kg and conclusions were extrapolated to all animal species. For 2‐pentylfuran [13.059], the Panel concluded that it is safe at the proposed maximum use level in feed of 0.5 mg/kg. No safety concern would arise for the consumer from the use of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] up to the proposed maximum use level in feed as flavourings. The additives should be considered as irritant to skin and eyes and the respiratory tract, and as dermal and respiratory sensitisers. The use of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] as flavours in animal feed was not expected to pose a risk for the environment. Since the compounds under assessment are used in food as flavourings and their function in feed is essentially the same as that in food, no further demonstration of efficacy was considered necessary. |
| format | Article |
| id | doaj-art-e7fbf7eb2f5d4c6f95e009bacbcfafa4 |
| institution | DOAJ |
| issn | 1831-4732 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj-art-e7fbf7eb2f5d4c6f95e009bacbcfafa42025-08-20T03:10:42ZengWileyEFSA Journal1831-47322023-03-01213n/an/a10.2903/j.efsa.2023.7868Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl)EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Vasileios BampidisGiovanna AzimontiMaria de Lourdes BastosHenrik ChristensenMojca DurjavaMaryline KoubaMarta López‐AlonsoSecundino López PuenteFrancesca MarconBaltasar MayoAlena PechováMariana PetkovaFernando RamosYolanda SanzRoberto Edoardo VillaRuud WoutersenPaul BrantomAndrew ChessonJohannes WestendorfPaola ManiniBirgit DusemundAbstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 (furfuryl and furan derivatives with and without additional side‐chain substituents and heteroatoms), when used as sensory additives (flavourings) in feed for all animal species. 2‐Acetylfuran [13.054] was tested in tolerance studies in chickens for fattening, weaned piglets and cattle for fattening. No adverse effects were observed in the tolerance studies at 10‐fold the intended use level. The FEEDAP Panel concluded that 2‐acetylfuran [13.054] is safe for these species at the proposed use level of 0.5 mg/kg and conclusions were extrapolated to all animal species. For 2‐pentylfuran [13.059], the Panel concluded that it is safe at the proposed maximum use level in feed of 0.5 mg/kg. No safety concern would arise for the consumer from the use of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] up to the proposed maximum use level in feed as flavourings. The additives should be considered as irritant to skin and eyes and the respiratory tract, and as dermal and respiratory sensitisers. The use of 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] as flavours in animal feed was not expected to pose a risk for the environment. Since the compounds under assessment are used in food as flavourings and their function in feed is essentially the same as that in food, no further demonstration of efficacy was considered necessary.https://doi.org/10.2903/j.efsa.2023.7868sensory additivesfeed flavouringsfuran derivatives2‐acetylfuran2‐pentylfuransafety |
| spellingShingle | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Paul Brantom Andrew Chesson Johannes Westendorf Paola Manini Birgit Dusemund Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl) EFSA Journal sensory additives feed flavourings furan derivatives 2‐acetylfuran 2‐pentylfuran safety |
| title | Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl) |
| title_full | Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl) |
| title_fullStr | Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl) |
| title_full_unstemmed | Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl) |
| title_short | Safety and efficacy of the feed additives 2‐acetylfuran [13.054] and 2‐pentylfuran [13.059] belonging to chemical group 14 for animal species (FEFANA asbl) |
| title_sort | safety and efficacy of the feed additives 2 acetylfuran 13 054 and 2 pentylfuran 13 059 belonging to chemical group 14 for animal species fefana asbl |
| topic | sensory additives feed flavourings furan derivatives 2‐acetylfuran 2‐pentylfuran safety |
| url | https://doi.org/10.2903/j.efsa.2023.7868 |
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