Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China

Abstract Background Implementing a full-sample prescription review system has become imperative for hospitals to address the limitations of post-review practices and ensure patient medication safety. In this study, we investigate the preliminary application impact of the prescription pre-review syst...

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Main Authors: Li Zhou, Xi Gu, Feilong Tan, Yanhua Li, Wenjing Duanmu, Hongyi Che, Fan Yang, Wenjie Yin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Health Services Research
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Online Access:https://doi.org/10.1186/s12913-025-12901-8
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author Li Zhou
Xi Gu
Feilong Tan
Yanhua Li
Wenjing Duanmu
Hongyi Che
Fan Yang
Wenjie Yin
author_facet Li Zhou
Xi Gu
Feilong Tan
Yanhua Li
Wenjing Duanmu
Hongyi Che
Fan Yang
Wenjie Yin
author_sort Li Zhou
collection DOAJ
description Abstract Background Implementing a full-sample prescription review system has become imperative for hospitals to address the limitations of post-review practices and ensure patient medication safety. In this study, we investigate the preliminary application impact of the prescription pre-review system (PPRS)and its rules maintenance in our hospital, while also evaluating the pharmaceutical service value resulting from the implementation of prescription pre-review. Methods We incorporated levels of prescribing warnings into the PPRS, while establishing and maintaining a database of appropriate medication practices. In addition, we evaluated the rationality of intravenous infusion prescriptions and key monitored drug prescriptions before and after the implementation of PPRS, and briefly evaluated the irrational prescriptions. Results A comprehensive range of 7 warning levels was established, reflective of the degree of prescription irrationality. Besides, a total of 3015 user rules were created to regulate medication behavior. The number and proportion of unreasonable prescriptions during January to March 2023 demonstrated a noteworthy reduction when compared to the corresponding period in 2022. Moreover, the continuous evaluation of systematic alert prescriptions during January to March 2023 indicated a remarkable monthly decline. Conclusion The introduction of the PPRS has ushered in a paradigm shift in the evaluation of prescription rationality. This transformative system has played a pivotal role in standardizing doctor’s prescribing patterns, thereby promoting the rational utilization of drugs in clinical practice. By ensuring patient safety, elevating the quality of care, and enhancing the value of pharmacists, the PPRS has emerged as a catalyst for positive change in the healthcare setting.
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spelling doaj-art-e7f1c0bcb75e4ef1a9f09e61cf8940ce2025-08-20T03:45:27ZengBMCBMC Health Services Research1472-69632025-07-0125111110.1186/s12913-025-12901-8Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in ChinaLi Zhou0Xi Gu1Feilong Tan2Yanhua Li3Wenjing Duanmu4Hongyi Che5Fan Yang6Wenjie Yin7Department of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityDepartment of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityDepartment of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityDepartment of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityDepartment of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityDepartment of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityJoint Surgery, General Hospital of Xizang Military CommandDepartment of Pharmacy, The Affiliated Yan’an Hospital of Kunming Medical UniversityAbstract Background Implementing a full-sample prescription review system has become imperative for hospitals to address the limitations of post-review practices and ensure patient medication safety. In this study, we investigate the preliminary application impact of the prescription pre-review system (PPRS)and its rules maintenance in our hospital, while also evaluating the pharmaceutical service value resulting from the implementation of prescription pre-review. Methods We incorporated levels of prescribing warnings into the PPRS, while establishing and maintaining a database of appropriate medication practices. In addition, we evaluated the rationality of intravenous infusion prescriptions and key monitored drug prescriptions before and after the implementation of PPRS, and briefly evaluated the irrational prescriptions. Results A comprehensive range of 7 warning levels was established, reflective of the degree of prescription irrationality. Besides, a total of 3015 user rules were created to regulate medication behavior. The number and proportion of unreasonable prescriptions during January to March 2023 demonstrated a noteworthy reduction when compared to the corresponding period in 2022. Moreover, the continuous evaluation of systematic alert prescriptions during January to March 2023 indicated a remarkable monthly decline. Conclusion The introduction of the PPRS has ushered in a paradigm shift in the evaluation of prescription rationality. This transformative system has played a pivotal role in standardizing doctor’s prescribing patterns, thereby promoting the rational utilization of drugs in clinical practice. By ensuring patient safety, elevating the quality of care, and enhancing the value of pharmacists, the PPRS has emerged as a catalyst for positive change in the healthcare setting.https://doi.org/10.1186/s12913-025-12901-8Prescription pre-reviewRules maintenanceWarning levelsPharmacist interventionRational drug use
spellingShingle Li Zhou
Xi Gu
Feilong Tan
Yanhua Li
Wenjing Duanmu
Hongyi Che
Fan Yang
Wenjie Yin
Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China
BMC Health Services Research
Prescription pre-review
Rules maintenance
Warning levels
Pharmacist intervention
Rational drug use
title Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China
title_full Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China
title_fullStr Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China
title_full_unstemmed Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China
title_short Establishment, maintenance and application effect analysis of the prescription pre-review system in a tertiary hospital in China
title_sort establishment maintenance and application effect analysis of the prescription pre review system in a tertiary hospital in china
topic Prescription pre-review
Rules maintenance
Warning levels
Pharmacist intervention
Rational drug use
url https://doi.org/10.1186/s12913-025-12901-8
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