B2M or CIITA knockdown decreased the alloimmune response of dental pulp stem cells: an in vitro study

B2M or CIITA knockdown decreased the alloimmune response of dental pulp stem cells: an in vitro study

Abstract Background Dental pulp stem cells (DPSCs) have acquired noteworthy attention for their application in treating ischemic diseases and facilitating tissue regeneration. However, the host’s immune response following allogenic DPSC transplantation often handicaps the long-term survival of trans...

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Main Authors: Mingxin Hu, Yuchen Zhang, Junqing Liu, Yihan Chen, Jun Kang, Jialin Zhong, Shulan Lin, Ye Liang, Rong Cen, Xiaofei Zhu, Chengfei Zhang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Dental pulp stem cells
Beta 2-microglobulin
Class II histocompatibility complex transactivator
Human leukocyte antigen
Immune rejection
Online Access:https://doi.org/10.1186/s13287-024-04023-5
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https://doi.org/10.1186/s13287-024-04023-5

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