Regulation of pyroptosis by NF-κB signaling

Regulation of pyroptosis by NF-κB signaling

Pyroptosis is a form of proinflammatory cell death characterized by inflammasome activation, pore formation, and the release of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and IL-18 upon cell rupture. Nuclear factor-κB (NF-κB), a prototypical pro-inflammatory transcription factor, play...

Full description

Saved in:

Bibliographic Details
Main Authors:	Ling Yang, Yan Zhang, Zhuodong Chai, Yuqi Zhou, Zhenyu Li, Yinan Wei
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Cell Death
Subjects:	pyroptosis NF-κB inflammasome infection inflammation
Online Access:	https://www.frontiersin.org/articles/10.3389/fceld.2024.1503799/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The involvement of CgCaspase-3 in regulating the expressions of proinflammatory cytokines through NF-κB/Rel signaling pathway in oysters
by: Zihan Wang, et al.
Published: (2025-06-01)

Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway
by: Lingchao Miao, et al.
Published: (2025-01-01)

Asperulosidic acid inhibits the PI3K/Akt/NF-κB pathway to suppress endotoxin-induced uveitis
by: Yong Du, et al.
Published: (2025-01-01)

ADAMDEC1 promotes the malignant progression of cholangiocarcinoma by regulating NF-κB signaling pathway
by: Shuo Zhou, et al.
Published: (2025-01-01)

Gedunin Mitigates <i>Cutibacterium acnes</i>-Induced Skin Inflammation by Inhibiting the NF-κB Pathway
by: Ju Kyoung Sim, et al.
Published: (2025-01-01)

The role of NF-κB in diabetic cardiomyopathy
by: Huang-Jun Liu, et al.
Published: (2024-12-01)

Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
by: Cheng Tan, et al.
Published: (2019-03-01)

BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis
by: He Qian, et al.
Published: (2024-12-01)

Assessing the influence of matcha green tea extract on NF-κB/MAPK signaling pathway activation in rats: A study on irradiation-induced acute hepatic inflammatory response
by: Noha Sayed Hamed, et al.
Published: (2025-02-01)

Downregulation of the immunoproteasome subunit PSMB8 attenuates sepsis-associated acute kidney injury through the NF-κB pathway
by: Min Li, et al.
Published: (2025-01-01)

Corrigendum: Ginkgolide C alleviates myocardial ischemia/reperfusion-induced inflammatory injury via inhibition of CD40-NF-κB pathway
by: Rui Zhang, et al.
Published: (2025-01-01)

Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis
by: Fanxuan Zhang, et al.
Published: (2025-01-01)

Anti-inflammatory effects of NaB and NaPc in Acinetobacter baumannii-stimulated THP-1 cells via TLR-2/NF-κB/ROS/NLRP3 pathway
by: Shu Chen, et al.
Published: (2022-12-01)

NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue
by: Letícia Aparecida Lopes Morgado, et al.
Published: (2025-01-01)

Decoding nature: multi-target anti-inflammatory mechanisms of natural products in the TLR4/NF-κB pathway
by: Yue Zhao, et al.
Published: (2025-01-01)

Apigenin ameliorates imiquimod-induced psoriasis in C57BL/6J mice by inactivating STAT3 and NF-κB
by: Xianshe Meng, et al.
Published: (2024-01-01)

Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway
by: Liang Xiao, et al.
Published: (2024-12-01)

LAMB1 downregulation suppresses glioma progression by inhibiting aerobic glycolysis through regulation of the NF-κB/HK2 axis
by: Zhenxiang Zhao, et al.
Published: (2025-02-01)

NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance
by: Shaoyan Shi, et al.
Published: (2025-01-01)

Regulator of G protein signaling-1 facilitates ovarian cancer development by modulating NF-kB signal pathway
by: Liu Shengnan, et al.
Published: (2025-01-01)

APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
by: Nora Hase, et al.
Published: (2025-01-01)

uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease
by: Yu Shen, et al.
Published: (2025-02-01)

NF-κB及IL-1ra在胃癌中的表达及其意义
Published: (2010-01-01)

Effect of Knee Arthritis Therapeutic Apparatus on Structure and NF-κB Inflammatory Pathway in Articular Cartilage of Rabbits with Knee Osteoarthritis
by: Guangwen WU, et al.
Published: (2016-04-01)

蟾毒灵抗炎镇痛作用及其对NF-κB信号通路的影响
Published: (2014-01-01)

Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation
by: Cao R, et al.
Published: (2025-02-01)

UGCG promotes chemoresistance and breast cancer progression via NF-κB and Wnt/β-catenin pathway activation
by: Li Long, et al.
Published: (2025-02-01)

Alone or in combination, hyaluronic acid and chondroitin sulfate alleviate ECM degradation in osteoarthritis by inhibiting the NF-κB pathway
by: Yiran Ma, et al.
Published: (2025-01-01)

Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway
by: Yumei Rong, et al.
Published: (2025-01-01)

Donkey whey proteins ameliorate dextran sulfate sodium-induced ulcerative colitis in mice by downregulating the S100A8-TRAF6-NF-κB axis-mediated inflammatory response
by: Mohan Li, et al.
Published: (2023-09-01)

Trim13‐induced ubiquitination of RPS27A inhibits the progression of lung cancer by depending on the inactivation of NF‐κB signaling pathway
by: Lailing Li, et al.
Published: (2024-12-01)

MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling
by: Wenshuai He, et al.
Published: (2025-01-01)

CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironment
by: Junfeng Xu, et al.
Published: (2025-03-01)

Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis
by: Liu Mengdan, et al.
Published: (2024-05-01)

Lawsonia intracellularis T3SS effector LI0758, an Rce1 ortholog, activates MAPK and NF-κB signaling in mammalian cells
by: Yuanxiu Zhong, et al.
Published: (2025-02-01)

Selenium-enriched oolong tea (Camellia sinensis) extract exerts anti-inflammatory potential via targeting NF-κB and MAPK pathways in macrophages
by: Qi Wang, et al.
Published: (2022-05-01)

Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism
by: Eman A. E. Farrag, et al.
Published: (2024-09-01)

Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways
by: Jing Huang, et al.
Published: (2025-01-01)

RETRACTED ARTICLE: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Snail signaling pathway in human gastric adenocarcinoma
by: Yaodong Zhu, et al.
Published: (2014-11-01)

GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis
by: Wen-Ke Wang, et al.
Published: (2024-12-01)