Unprecedented in vivo activity of telacebec against Mycobacterium leprae.

<h4>Background</h4>New drugs targeting the electron transport chain (ETC) seem to be a promising advance in leprosy treatment. In this study, we evaluated the bactericidal activity of telacebec (TCB), a phase 2 drug candidate for tuberculosis, alongside known ETC-targeting antibiotics, b...

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Bibliographic Details
Main Authors: Aurélie Chauffour, Emmanuelle Cambau, Kevin Pethe, Nicolas Veziris, Alexandra Aubry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0013076
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