Iron metabolism and ferroptosis in human health and disease

Abstract Iron is indispensable to most lifeforms, underpinning a myriad of physiological processes. Dysregulation of iron homeostasis underlies a broad spectrum of biological phenomena and pathological conditions. Notably, excessive iron overload acts as a key driver of ferroptosis, a unique form of...

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Bibliographic Details
Main Authors: Meijuan Zhong, Yuandi Wang, Junxia Min, Fudi Wang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02378-6
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