Substrate engineering using naturally biomimicking corneal cell topography for preserving stemness of corneal limbal epithelial-stem cells

Substrate engineering using naturally biomimicking corneal cell topography for preserving stemness of corneal limbal epithelial-stem cells

Objective(s): Substrate engineering is one of the attractive fields of changing cell behavior and fate, especially for stem cell (SC) therapies. The SC pool is an essential factor in transplantation outcomes. Here, the objective was to preserve the stemness of the cornea’s limbal epithelial stem cel...

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Main Authors: Tahereh Manoochehrabadi, Ali Samadikuchaksaraei, Amin Solouki, Seyed-Hashem Daryabari, Hamed Ghasemi, Ehsan Lotfi, Sajad Mansourian, Jila Majidi, Peiman Brouki Milan, Mazaher Gholipourmalekabadi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-07-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
cell-imprinting
cell therapy
corneal epithelium
corneal topography limbal stem cell polydimethylsiloxane substrate engineering
Online Access:https://ijbms.mums.ac.ir/article_25931_5dde66735d59dcb3df13b8bc9a2fe368.pdf
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