Development, validation and application of a high-performance liquid chromatography method for the detection of ibuprofen in elephant plasma

Development, validation and application of a high-performance liquid chromatography method for the detection of ibuprofen in elephant plasma

A simple and accurate method for the determination of ibuprofen concentrations in elephant plasma was developed and validated using reverse phase high-performance liquid chromatography (HPLC). Utilizing a liquid-liquid extraction with ethyl acetate, methanol, and phosphoric acid, samples were separa...

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Bibliographic Details
Main Authors: Sherry Cox, Aaron Bloom, Riley Golias, Madeline Duncan, Joan Bergman, Andrew Cushing
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Ibuprofen
Plasma
Ultraviolet detection
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024151766
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