Screening and identification of host factors interacting with the nucleocapsid protein of SARS-CoV-2 omicron variant using the yeast two-hybrid system

Screening and identification of host factors interacting with the nucleocapsid protein of SARS-CoV-2 omicron variant using the yeast two-hybrid system

Abstract Background The nucleocapsid protein (N protein) of SARS-CoV-2 is highly conserved in viral evolution and serves as the primary structural protein in viral infection, being the most abundant in viral particles. The N protein is highly immunogenic and plays a key role in the processes of vira...

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Bibliographic Details
Main Authors: Chunhua Wang, Tingyu Yu, Moyue Xie, Dongang Zhan, Shuaijie Zhang, Wenqi Chai, Jianzhong Zhao, Lijuan Yin, Yang Yang, Liang Shen, Ying Xia
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Microbiology
Subjects:
SARS-CoV-2
Nucleocapsid
RNF2
ARL15
Yeast two-hybrid system
Online Access:https://doi.org/10.1186/s12866-025-04226-7
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