Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters

Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters

Saved in:

Bibliographic Details
Main Authors:	Levi Tamming, Diana Duque, Anh Tran, Casey Lansdell, Grant Frahm, Jianguo Wu, Emily E.F. Fekete, Marybeth Creskey, Sathya N. Thulasi Raman, Emmanuel Laryea, Wanyue Zhang, Annabelle Pfeifle, Caroline Gravel, Andrew Stalker, Anwar M. Hashem, Wangxue Chen, Matthew Stuible, Yves Durocher, David Safronetz, Jingxin Cao, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Xu Zhang, Michael J.W. Johnston, Xuguang Li
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	Molecular Therapy: Methods & Clinical Development
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050124002043
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Novel recombinant vaccinia virus-vectored vaccine affords complete protection against homologous Borrelia burgdorferi infection in mice
by: Annabelle Pfeifle, et al.
Published: (2024-12-01)

Dissecting immunological mechanisms underlying influenza viral nucleoprotein-induced mucosal immunity against diverse viral strains
by: Wanyue Zhang, et al.
Published: (2024-12-01)

Diaphragm Structure and Function in Emphysematous Hamsters
by: WD Reid, et al.
Published: (1994-01-01)

Decreased neuronal excitability in hypertriglyceridemia hamsters with acute seizures
by: Qiuyue Shen, et al.
Published: (2024-12-01)

Development of a hamster model of spontaneous hypertriglyceridemia in diabetes
by: Ya‐Hong Ma, et al.
Published: (2024-12-01)

Hamster and Murine Models of Severe Destructive Lyme Arthritis
by: Erik Munson, et al.
Published: (2012-01-01)

Histopathology of the tongue in a hamster model of COVID-19
by: John Coggins, et al.
Published: (2025-01-01)

Cytotoxicity and Genotoxicity of Panel of Single- and Multiwalled Carbon Nanotubes: In Vitro Effects on Normal Syrian Hamster Embryo and Immortalized V79 Hamster Lung Cells
by: C. Darne, et al.
Published: (2014-01-01)

Altered Expression of Cellular Bcl-2 in the Progression of Hamster Cholangiocarcinogenesis
by: Byung-suk Jeon, et al.
Published: (2012-01-01)

Leukotriene inhibition in hamster periodontitis. A histochemical and morphometric study
by: B. Baroukh, et al.
Published: (1992-01-01)

Antinociceptive effect of Equisetum arvense extract on the stomatitis hamster model.
by: Fumie Shiba, et al.
Published: (2024-01-01)

A biomathematical model of SARS-CoV-2 in Syrian hamsters
by: Sibylle Schirm, et al.
Published: (2024-12-01)

Changes in Mobility of the Golden Hamster with Induction of an IL-1-Induced Arthritis
by: I. G. Otterness, et al.
Published: (1994-01-01)

The feasibility of establishing a hamster model for HBV infection: in vitro evidence
by: Hu Zhang, et al.
Published: (2024-11-01)

Comparison of the Fixation Effects of Six Composite Fixatives on Retinal Tissue of Golden Hamsters
by: WU Haifeng, et al.
Published: (2024-12-01)

Expression and functional characterization of His-tagged prestin in Chinese hamster ovary cells.
by: Ryosei Motoo, et al.
Published: (2024-01-01)

The morphofunctional and biochemical characteristics of opisthorchiasis-associated cholangiocarcinoma in a Syrian hamster model
by: G. A. Maksimova, et al.
Published: (2015-12-01)

Cause and Possible Treatments of Foot Lesions in Captive Syrian Hamsters (Mesocricetus auratus)
by: Mélisa Veillette, et al.
Published: (2010-01-01)

Expression and functional characterization of His-tagged prestin in Chinese hamster ovary cells
by: Ryosei Motoo, et al.
Published: (2024-01-01)

Metabolism and immune responses of striped hamsters to ectoparasite challenges: insights from transcriptomic analysis
by: Xinchang Lun, et al.
Published: (2024-12-01)

High-flow oxygen for children’s airway surgery: randomised controlled trial protocol (HAMSTER)
by: Julia Taylor, et al.
Published: (2019-10-01)

Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies
by: Ying Bai, et al.
Published: (2025-01-01)

Effectiveness of Polyclonal Antibody Immunoconjugate Treatment with Propamidine Isethionate for Amoebic Keratitis in Golden Hamsters
by: Manuel Enrique Ávila-Blanco, et al.
Published: (2023-01-01)

Effect of Gelam Honey on the Oxidative Stress-Induced Signaling Pathways in Pancreatic Hamster Cells
by: Kalaivani Batumalaie, et al.
Published: (2013-01-01)

Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters
by: Yongjun Sui, et al.
Published: (2025-02-01)

Assessment of Favipiravir and Remdesivir in Combination for SARS-CoV-2 Infection in Syrian Golden Hamsters
by: Megan Neary, et al.
Published: (2024-11-01)

Syrian hamsters (Mesocricetus auratus) as an upper respiratory tract model for respiratory syncytial virus infection
by: Sophie M. Kolbe, et al.
Published: (2025-01-01)

Phenotyping the virulence of SARS-CoV-2 variants in hamsters by digital pathology and machine learning.
by: Gavin R Meehan, et al.
Published: (2023-11-01)

Friend or foe? Engaging public can save the critically endangered common hamster (Cricetus cricetus)
by: Julianna Szulamit Szapu, et al.
Published: (2024-09-01)

Reduced cross-protective potential of Omicron compared to ancestral SARS-CoV-2 spike vaccines against potentially zoonotic coronaviruses
by: Tyler M. Renner, et al.
Published: (2024-11-01)

Perineuronal Nets in Syrian Hamsters: Anatomical Localization, Sex Differences, Diurnal Variation, and Response to Social Stress
by: Emma K. Shaughnessy, et al.
Published: (2024-12-01)

ApoL1 risk allele accelerates high-fat diet-induced atherosclerosis in LDLR−/− hamsters
by: Yitong Xu, et al.
Published: (2025-03-01)

Fully human monoclonal antibodies against Ebola virus possess complete protection in a hamster model
by: Wujian Li, et al.
Published: (2024-12-01)

Functional and structural characterization of HspB1/Hsp27 from Chinese hamster ovary cells
by: Eiryo Sha, et al.
Published: (2019-10-01)

Wild Brazilian yellow fever virus infection in Syrian hamsters (Mesocricetus auratus): Clinical and histopathological analyses
by: Fernanda de Oliveira Bottino, et al.
Published: (2024-12-01)

Gut microbiota and quantitative traits divergence at different altitude of long-tailed dwarf hamsters, Cricetulus longicaudatus
by: Yue Ren, et al.
Published: (2025-01-01)

Phylogenetic relationships of Neogene hamsters (Mammalia, Rodentia, Cricetinae) revealed under Bayesian inference and maximum parsimony
by: Moritz Dirnberger, et al.
Published: (2024-11-01)

The Kilbrandon report and disabled children: some reflections 50 years on
by: Kirsten Stalker
Published: (2014-12-01)

Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster
by: Ren-Di Jiang, et al.
Published: (2025-02-01)

Characterization of a SARS-CoV-2 Omicron BA.5 direct-contact transmission model in hamsters
by: Kim Handrejk, et al.
Published: (2024-11-01)